Results 61 to 70 of about 26,575,973 (337)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

The impact of urban conditions on different tree species in public green areas in the city of Poznan

open access: yesFolia Horticulturae, 2015
Parks in urbanised areas fulfil an important function as they create a positive climate in cities and contribute to the good health of their inhabitants.
Krzyżaniak Michał   +3 more
doaj   +1 more source

Shunt active DC filter based on intelligence controller for HVDC link

open access: yesHigh Voltage, 2017
A shunt active DC filter (ADF) with current injection suppresses current harmonics from high-voltage DC (HVDC) transmission systems. This paper proposes an ADF based on artificial neural networks (ANNs). The ANNs are very generic, accurate and convenient
Seyedreza Aali
doaj   +1 more source

A Statistical Model for Helices with Applications [PDF]

open access: yesBiometrics, 2018
Summary Motivated by a cutting edge problem related to the shape of -helices in proteins, we formulate a parametric statistical model, which incorporates the cylindrical nature of the helix. Our focus is to detect a “kink,” which is a drastic change in the axial direction of the helix.
Mardia, KV, Sriram, K, Deane, CM
openaire   +4 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Statistical Modeling of SAR Images: A Survey

open access: yesSensors, 2010
Statistical modeling is essential to SAR (Synthetic Aperture Radar) image interpretation. It aims to describe SAR images through statistical methods and reveal the characteristics of these images.
Gui Gao
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

A global optimization method based on the reduced simplicial statistical model

open access: yesMathematical Modelling and Analysis, 2011
A simplicial statistical model of multimodal functions is used to construct a global optimization algorithm. The search for the global minimum in the multidimensional space is reduced to the search over the edges of simplices covering the feasible region
Antanas Žilinskas, Julius Žilinskas
doaj   +1 more source

On the statistical identification of DSGE models [PDF]

open access: yesJournal of Econometrics, 2009
Dynamic Stochastic General Equilibrium (DSGE) models are now considered attractive by the profession not only from the theoretical perspective but also from an empirical standpoint. As a consequence of this development, methods for diagnosing the fit of these models are being proposed and implemented.
Consolo, Agostino.   +2 more
openaire   +6 more sources

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