Results 71 to 80 of about 15,562,972 (297)

Performance Evaluation of Shiryaev–Roberts and Cumulative Sum Schemes for Monitoring Shape and Scale Parameters in Gamma-Distributed Data Under Type I Censoring

Axioms
This paper proposes two process monitoring schemes, namely the Shiryaev–Roberts (SR) procedure and the cumulative sum (CUSUM) procedure, to detect shifts in the shape and scale parameters of Type I right-censored Gamma-distributed lifetime data.
He Li, Peile Chen, Ruicheng Ma, Jiujun Zhang   +3 more
doaj   +1 more source

Multivariate statistical process monitoring

Tehnički vjesnik = Technical gazette, 2012
Demands regarding production efficiency, product quality, safety levels and environment protection are continuously increasing in the process industry. The way to accomplish these demands is to introduce the more complex automatic control systems which require more process variables to be measured and more advanced measurement systems.
Hocenski, Željko, Grbić, Ratko, Slišković, Dražen   +2 more
openaire   +1 more source

Multivariate Statistical Process Control Charts: An Overview [PDF]

In this paper we discuss the basic procedures for the implementation of multivariate statistical process control via control charting. Furthermore, we review multivariate extensions for all kinds of univariate control charts, such as multivariate ...
Bersimis, Sotiris, Panaretos, John, Psarakis, Stelios   +2 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

On the implementation and performance assessment of an assumption-free methodology for batch process monitoring [PDF]

openBatch process monitoring is a challenging task due to the high variability of these type of processes. In order to ensure that the final product is of prescribed quality, statistical techniques have been developed for monitoring the process.
DI CARLO, GIULIO
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Multivariate Statistical Process Control Charts and the Problem of Interpretation: A Short Overview and Some Applications in Industry [PDF]

Woodall and Montgomery in a discussion paper, state that multivariate process control is one of the most rapidly developing sections of statistical process control.
Bersimis, Sotiris, Panaretos, John, Psarakis, Stelios   +2 more
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source