Results 131 to 140 of about 573,105 (295)

Statistical Shape Model for robotic spine surgery

The goal of the project is to generate a 3D model of the C2 cervical vertebra for surgery planning using an atlas-based segmentation technique. A Statistical Shape Model of the C2 vertebra has been created from 91 CT scans using Statismo [1], a toolkit ...
Clogenson, Marine, Baur, Charles
core  

Inferring 3D finger bone shapes from 2D images – a detailed analysis of shape accuracy

Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization
3D visualisation and modelling of anatomical structures of the human body play a significant role in diagnosis, computer-aided surgery, surgical planning, and patient follow-up. However, 2D X-ray images are often used in clinical routine.
Anna Rörich, Annkristin Lange, Stefan Heldmann, Jan H. Moltz, Lars Walczak, Sinef Yarar-Schlickewei, Felix Güttler, Joachim Georgii   +7 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

GPU accelerated registration of a statistical shape model of the lumbar spine to 3D ultrasound images

, 2011
We present a parallel implementation of a statistical shape model registration to 3D ultrasound images of the lumbar vertebrae (L2-L4). Covariance Matrix Adaptation Evolution Strategy optimization technique, along with Linear Correlation of Linear ...
Khallaghi, S., Gill, S., Mousavi, P., Fichtinger, Gabor, Chen, Elvis C. S., Borschneck, Dan, Siavash Khallaghi, Abolmaesumi, P., Boisvert, J., Mousavi, Parvin, Ren Hui Gong, Borschneck, D., Chen, E., Gill, Sean, Gong, R.H., Jonathan Boisvert, Boisvert, Jonathan, David Pichora, Dan Borschneck, Pichora, David, Purang Abolmaesumi, Gabor Fichtinger, Gong, Ren Hui, Fichtinger, G., Pichora, D., Abolmaesumi, Purang, Elvis Chen, Parvin Mousavi, Khallaghi, Siavash, Sean Gill   +29 more
core   +1 more source

[Three-dimensional reconstruction of femur based on Laplace operator and statistical shape model]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2023
Zhang Z, Zhang X, Zhang Y, Jin Z.
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

An Exploratory Statistical Shape Modeling Analysis of Three‐Dimensional Foot Alignment in Female Patients With Progressive Collapsing Foot Deformity

Journal of Foot and Ankle Research
Introduction Progressive collapsing foot deformity (PCFD) is a complex condition characterized by multiple combined deformities, with a higher reported prevalence in women.
Takuma Miyamoto, Rich J. Lisonbee, Kassidy Knutson, Hiroaki Kurokawa, Akira Taniguchi, Yasuhito Tanaka, Amy L. Lenz   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source