Results 91 to 100 of about 440,016 (278)

Predictive properties of statistical shape models

, 2011
Selected readings in vision and graphics ...
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Development and validation of statistical shape models of the primary functional bone segments of the foot.

, 2019
This dataset comprises manually segmented three-dimensional point clouds (.STL) of magnetic resonance images of the primary functional segments of the foot - first metatarsal, midfoot (second-to-fifth metatarsals, cuneiforms, cuboid, and navicular ...
Diamond, Laura (8178330), Maharaj, Jayishni, Maharaj, Jayishni (8178345), Grant, Tamara, Pizzolato, Claudio, Killen, Bryce, Kelly, Luke, Grant, Tamara (8178327), Diamond, Laura, Devaprakash, Daniel (8178339), Killen, Bryce (8178336), Pizzolato, Claudio (8178333), Saxby, David (8178348), Saxby, David, Devaprakash, Daniel, Kelly, Luke (8178342)   +15 more
core   +1 more source

Opening Up the "Black Box" of Medical Image Segmentation with Statistical Shape Models

, 2013
The importance of medical image segmentation increases in fields like treatment planning or computer aided diagnosis. For high quality automatic segmentations, algorithms based on statistical shape models (SSMs) are often used.
Landesberger von Antburg, Tatiana, Kirschner, Matthias, Wesarg, Stefan, Kuijper, Arjan, Andrienko, Gennady, Bremm, Sebastian, Andrienko, Natalia   +6 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Functional constraints on tooth morphology in carnivorous mammals

BMC Evolutionary Biology, 2012
Background The range of potential morphologies resulting from evolution is limited by complex interacting processes, ranging from development to function.
Smits Peter D, Evans Alistair R
doaj   +1 more source

Can point cloud networks learn statistical shape models of anatomies? [PDF]

Med Image Comput Comput Assist Interv, 2023
Adams J, Elhabian S.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Novel Self-Intersection Penalty Term for Statistical Body Shape Models and Its Applications in 3D Pose Estimation

Applied Sciences, 2019
Statistical body shape models are widely used in 3D pose estimation due to their low-dimensional parameters representation. However, it is difficult to avoid self-intersection between body parts accurately.
Zaiqiang Wu, Wei Jiang, Hao Luo, Lin Cheng   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source