Results 101 to 110 of about 440,016 (278)

Conditional variability of statistical shape models based on surrogate variables [PDF]

, 2009
International audienceWe propose to increment a statistical shape model with surrogate variables such as anatomical measurements and patient-related information, allowing conditioning the shape distribution to follow prescribed anatomical constraints ...
Blanc, R., Christof Seiler, Rémi Blanc, Mauricio Reyes, Gábor Székely, Reyes, Mauricio, Blanc, Remi, Székely, Gabor, Seiler, Christof, Székely, G.   +9 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Testing the Utility of a Data-Driven Approach for Assessing BMI from Face Images.

PLoS ONE, 2015
Several lines of evidence suggest that facial cues of adiposity may be important for human social interaction. However, tests for quantifiable cues of body mass index (BMI) in the face have examined only a small number of facial proportions and these ...
Karin Wolffhechel, Amanda C Hahn, Hanne Jarmer, Claire I Fisher, Benedict C Jones, Lisa M DeBruine   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Statistical Shape Modeling of Skeletal Anatomy for Sex Discrimination: Their Training Size, Sexual Dimorphism, and Asymmetry

Frontiers in Bioengineering and Biotechnology, 2019
Purpose: Statistical shape modeling provides a powerful tool for describing and analyzing human anatomy. By linearly combining the variance of the shape of a population of a given anatomical entity, statistical shape models (SSMs) identify its main modes
E. A. Audenaert, E. A. Audenaert, E. A. Audenaert, C. Pattyn, G. Steenackers, J. De Roeck, D. Vandermeulen, D. Vandermeulen, P. Claes, P. Claes, P. Claes, P. Claes, P. Claes   +12 more
doaj   +1 more source

Image2SSM: Reimagining Statistical Shape Models from Images with Radial Basis Functions. [PDF]

Med Image Comput Comput Assist Interv, 2023
Xu H, Elhabian SY.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Three-dimensional magnetic resonance imaging-based statistical shape analysis and machine learning-based prediction of patellofemoral instability

Scientific Reports
This study performed three-dimensional (3D) magnetic resonance imaging (MRI)-based statistical shape analysis (SSA) by comparing patellofemoral instability (PFI) and normal femur models, and developed a machine learning (ML)-based prediction model ...
Keita Nagawa, Kaiji Inoue, Yuki Hara, Hirokazu Shimizu, Saki Tsuchihashi, Koichiro Matsuura, Eito Kozawa, Naoki Sugita, Mamoru Niitsu   +8 more
doaj   +1 more source

Accurate and Efficient Segmentation of Optic Disc and Optic Cup in Retinal Images Integrating Multi-View Information

IEEE Access, 2019
Glaucoma is an eye disease which is one of the most common causes of blindness. Accurate optic disc (OD) and optic cup (OC) segmentation play a critical role for detecting glaucoma. Considering that the existing approaches can't effectively integrate the
Yuan Gao, Xiaosheng Yu, Chengdong Wu, Wei Zhou, Xiaonan Wang, Hao Chu   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source