Results 191 to 200 of about 5,852,793 (269)

Beyond statistical significance: Embracing minimal clinically important difference for better patient care. [PDF]

World J Methodol
Jeyaraman N, Jeyaraman M, Ramasubramanian S, Balaji S, Muthu S.   +4 more
europepmc   +1 more source

On the statistical significance of communities from weighted graphs. [PDF]

Sci Rep, 2021
He Z, Chen W, Wei X, Liu Y.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Structure matters: Assessing the statistical significance of network topologies. [PDF]

PLoS One
Salbanya B, Carrasco-Farré C, Nin J.
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Science is judgment, not only calculation

Erasmus Journal for Philosophy and Economics, 2008
Stephen T. Ziliak, Deirdre Nansen McCloskey   +1 more
doaj   +1 more source

How the quality of GWAS of human lifespan and health span can be improved

Frontiers in Genetics, 2013
Anatoliy I Yashin, Konstantin G. Arbeev, Deqing eWu, Liubov S. Arbeeva, Alexander M Kulminski, Igor eAkushevich, Irina eCulminskaya, Eric eStallard, Svetlana eUkraintseva   +8 more
doaj   +1 more source

Corrigendum to "About Research: Clinical Versus Statistical Significance". [PDF]

J Hum Lact
europepmc   +1 more source

The difference between clinical significance and statistical significance: an important distinction for clinical research. [PDF]

Turk J Med Sci
Elasan S.
europepmc   +1 more source