Results 71 to 80 of about 6,116,423 (300)
Some uses of predictive probability of success in clinical drug development
Epidemiology, Biostatistics and Public Health, 2013 Predictive probability of success is a (subjective) Bayesian evaluation of the prob- ability of a future successful event in a given state of information. In the context of pharmaceutical clinical drug development, successful events relate to the accrual
Mauro Gasparini +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
The role of statistical methodology in simulation [PDF]
statistical methods;simulation;operations ...
Kleijnen, J.P.C.
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Statistical analysis of chemical computational systems with MULTIVESTA and ALCHEMIST [PDF]
, 2013 The chemical-oriented approach is an emerging paradigm for programming the behaviour of densely distributed and context-aware devices (e.g. in ecosystems of displays tailored to crowd steering, or to obtain profile-based coordinated visualization ...
Sebastio, Stefano +2 more
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Statistical Mechanics of Nonequilibrium Liquids [PDF]
, 2007 "There is a symbiotic relationship between theoretical nonequilibrium statistical mechanics on the one hand and the theory and practice of computer simulation on the other.
Evans, Denis J +8 more
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Statistical aspects of simulation: an updated survey* [PDF]
Statistica Neerlandica, 1982 Abstract Practical statistical techniques for the design and analysis of simulation experiments are presented. These techniques are relevant in both discrete and continuous, deterministic and stochastic simulation. To generalize and interpret the simulation output the analyst can use regression analysis.
openaire +4 more sources
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
An Object-Oriented Framework for Statistical Simulation: The R Package simFrame [PDF]
Simulation studies are widely used by statisticians to gain insight into the quality of developed methods. Usually some guidelines regarding, e.g., simulation designs, contamination, missing data models or evaluation criteria are necessary in order to ...
Andreas Alfons +2 more
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Statistical simulation procedures [PDF]
, 1970 Statistical simulation procedures utilizing Monte Carlo stratification ...
Tremelling, R. N., II +3 more
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