Results 81 to 90 of about 8,661,639 (296)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Reviews of Free Statistical Software [PDF]
Interdisciplinary Journal of Virtual Learning in Medical Sciences, 2014 Nowadays the use of statistical software is obvious to conduct scientific research. Select statistical software according to moral considerations requires payment of fees.
Rahil Hakimimofrad, Reza Hakimimofrad
doaj
, 2023 https://github.com/CITCOM-project/CausalTestingFrameworkCausal testing is a causal inference-driven framework for functional black-box testing. This framework utilises graphical causal inference (CI) techniques for the specification and functional ...
Christopher Wild (9685985) +8 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
SSN & STARS: Tools for Spatial Statistical Modeling on Stream Networks
, 2019 Spatial statistical models for streams provide a new set of analytical tools that can be used to improve predictions of physical, chemical, and biological characteristics on stream networks.
Erin Peterson (2718091) +1 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Statistical Testing on Prediction of Software Defects
EAI Endorsed Transactions on Energy Web, 2018 Statistical Tests are used to make inferences from data. These tests will tell whether the observed pattern is real or just due to chance. The type of the test, to be used, depends on research design, distribution of data and type of variables.
Satya Srinivas Maddipati +1 more
doaj +1 more source
Accuracy Test of Software Architecture Compliance Checking Tools – Test Instruction [PDF]
, 2015 Software Architecture Compliance Checking (SACC) is an approach to verify conformance of implemented program code to high-level models of architectural design.
Brinkkemper., Sjaak +4 more
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source