Results 101 to 110 of about 8,655,439 (299)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Pooling individual samplesWhy Is This Important?

open access: yesJADA Foundational Science, 2022
Carissa Comnick, MS   +2 more
doaj   +1 more source

Characteristics and Spending Patterns of Consumer Units in the Lowest 10 Percent of the Expenditure Distribution [PDF]

open access: yes, 2001
How do poor consumers differ from the average consumer? Typically, consumers’ ability to purchase goods and services is measured by their income, and consumers are classified as “poor” if their income falls below some standard level, such as the poverty ...
Bureau of Labor Statistics
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Frequentist, Bayesian Analysis and Complementary Statistical Tools for Geriatric and Rehabilitation Fields: Are Traditional Null-Hypothesis Significance Testing Methods Sufficient?

open access: yesClinical Interventions in Aging
Dahan da Cunha Nascimento,1,* Nicholas Rolnick,2,* Isabella da Silva Almeida,3,* Gerson Cipriano Junior,4,* João Luiz Durigan3,* 1Physical Education Department, Universidade Católica de Brasília, Brasília, DF, Brazil; 2The Human ...
Nascimento DDC   +4 more
doaj  

APPLYING STATISTICAL ANALYSIS TO DETERMINE NUMBER OF COFFEE SHOPS

open access: yesВестник Северо-Кавказского федерального университета, 2022
The consumer market of goods and services is one of the main and important components of the structure of the modern economy. It is here that the daily needs of the population are realized, the level of satisfaction of which, in the final analysis ...
N. Cheremisina   +2 more
doaj  

1960 Statistics

open access: yes, 1960
1960 Men\u27s Basketball Statistics, George Fox ...
George Fox University Archives
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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