Results 41 to 50 of about 6,999,060 (353)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

ICT Employment Statistics in Europe: Measuring Methodology [PDF]

open access: yes, 2013
Despite the persistent need to precisely capture and carefully analyze the employment effects associated with the production and deployment of ICT, policy discussion has not been well-supported by good quality statistical information on the ICT ...
SABADASH GANNA
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

The Effect of the Financial Crisis on the Taxation of Consumption, Labour, and Capital in the European Union [PDF]

open access: yes, 2013
4. For the purpose of this paper we used statistics prepared according to the methodology adopted by the European Commission, published in “Taxation trends in the European Union”, Eurostat 2012.Materiały statystyczne wykorzystane w artykule pochodzą z ...
Krajewska, Anna
core   +2 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Towards Improving the Export Price Index [PDF]

open access: yes
This paper examines the methodology for computing the export price index used by the National Census and Statistics Office, evaluates this methodology and the problems arising from its use, discusses an alternative methodology and proposes the adoption ...
Cantillep, Arturo Jr., Reyes, Celia M
core   +2 more sources

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Deferred statistical order convergence in Riesz spaces [PDF]

open access: yesarXiv, 2022
Some types of statistical convergence such as statistical order and deferred statistical convergences have been studied and investigated in Riesz spaces, recently. In this paper, we introduce the concept of deferred statistical convergence in Riesz spaces with order convergence.
arxiv  

Rejoinder: Classifier Technology and the Illusion of Progress [PDF]

open access: yesStatistical Science 2006, Vol. 21, No. 1, 30-34, 2006
Rejoinder: Classifier Technology and the Illusion of Progress [math.ST/0606441]
arxiv   +1 more source

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