Results 71 to 80 of about 631,153 (290)

Stability Estimates for Finite-Dimensional Distributions of Time-Inhomogeneous Markov Chains

Mathematics, 2020
This paper is devoted to the study of the stability of finite-dimensional distribution of time-inhomogeneous, discrete-time Markov chains on a general state space.
Vitaliy Golomoziy, Yuliya Mishura
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Math 311 Statistics and Probability in Elementary Mathematics [PDF]

, 2013
MATH 311, Statistics and Probability in Elementary Mathematics (2)\ud Prerequisites: Mathematics 211 and satisfactory performance on Mathematics Departmental Placement Examination, Part LS.\ud Topics from statistics and probability. Enrollment limited
Siegfried, John
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Optimal stopping under probability distortion [PDF]

, 2013
We formulate an optimal stopping problem for a geometric Brownian motion where the probability scale is distorted by a general nonlinear function. The problem is inherently time inconsistent due to the Choquet integration involved.
Xu, Z, Xu, ZQ, Zhou, XY
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Introduction to Probability, Statistics and Random Processes [PDF]

, 2014
Creative Commons Attribution-NonCommercial-NoDerivsIntroduction to Probability, Statistics, and Random Processes is an open access peer-reviewed textbook intended for undergraduate as well as first-year graduate level courses on the subject.
Pishro-Nik, Hossein
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ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The Existence, Uniqueness, and Controllability of Neutral Stochastic Delay Partial Differential Equations Driven by Standard Brownian Motion and Fractional Brownian Motion

Discrete Dynamics in Nature and Society, 2018
We focus on a class of neutral stochastic delay partial differential equations perturbed by a standard Brownian motion and a fractional Brownian motion.
Dehao Ruan, Jiaowan Luo
doaj   +1 more source

Improved Probability-Weighted Moments and Two-Stage Order Statistics Methods of Generalized Extreme Value Distribution [PDF]

This study evaluates six parameter estimation methods for the generalized extreme value (GEV) distribution: maximum likelihood estimation (MLE), two probability-weighted moments (PWM-UE and PWM-PP), and three robust two-stage order statistics estimators (
Autcha Araveeporn
core   +1 more source

Assessing the quality of bootstrap samples and of the bootstrap estimates obtained with finite resampling [PDF]

, 2002
Statistics and Probability Letters594281 ...
Yatracos, Yannis G., Yatracos, Y.
core   +1 more source