Results 101 to 110 of about 2,998,558 (396)

Creating and using real-world evidence to answer questions about clinical effectiveness

open access: yesJournal of Innovation in Health Informatics, 2015
New forms of evidence are needed to complement evidence generated from randomised controlled trials (RCTs). Real-World Evidence (RWE) is a potential new form of evidence, but remains undefined.This paper sets to fill that gap by defining RWE as the ...
Simon de Lusignan   +2 more
doaj   +1 more source

A Coefficient of Determination for Probabilistic Topic Models [PDF]

open access: yesarXiv, 2019
This research proposes a new (old) metric for evaluating goodness of fit in topic models, the coefficient of determination, or $R^2$. Within the context of topic modeling, $R^2$ has the same interpretation that it does when used in a broader class of statistical models. Reporting $R^2$ with topic models addresses two current problems in topic modeling:
arxiv  

Nanomaterials for Supercapacitors: Uncovering Research Themes with Unsupervised Machine Learning [PDF]

open access: yesarXiv, 2022
Identification of important topics in a text can facilitate knowledge curation, discover thematic trends, and predict future directions. In this paper, we aim to quantitatively detect the most common research themes in the emerging supercapacitor research area, and summarize their trends and characteristics through the proposed unsupervised, machine ...
arxiv  

Statistical models for topic segmentation [PDF]

open access: yesProceedings of the 37th annual meeting of the Association for Computational Linguistics on Computational Linguistics -, 1999
Most documents are about more than one subject, but many NLP and IR techniques implicitly assume documents have just one topic. We describe new clues that mark shifts to new topics, novel algorithms for identifying topic boundaries and the uses of such boundaries once identified.
openaire   +2 more sources

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1155-1169, April 2025.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park   +8 more
wiley   +1 more source

Medical graduate views on statistical learning needs for clinical practice: a comprehensive survey

open access: yesBMC Medical Education, 2019
Background This paper seeks to contribute to a reputable evidence base for required competencies across different topics in statistics and probability (statistical topics) in preparing medical graduates for clinical practice.
Margaret MacDougall   +2 more
doaj   +1 more source

Prior-aware Dual Decomposition: Document-specific Topic Inference for Spectral Topic Models [PDF]

open access: yesarXiv, 2017
Spectral topic modeling algorithms operate on matrices/tensors of word co-occurrence statistics to learn topic-specific word distributions. This approach removes the dependence on the original documents and produces substantial gains in efficiency and provable topic inference, but at a cost: the model can no longer provide information about the topic ...
arxiv  

Books or Baskets: Compromising the Education and Future of Black Student-Athletes [PDF]

open access: yes, 2018
In this paper, I discuss the challenges and inequalities that Black male athletes face while playing college sports, particularly basketball and football at PWIs.
Laemle, Jessica L.
core   +1 more source

Current Topics in Statistical Graphics

open access: yesRevista Colombiana de Estadística, 2014
Refereed/Peer ...
openaire   +3 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

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