Results 81 to 90 of about 1,692,958 (373)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Adaptive Nonparametric Regression on Spin Fiber Bundles [PDF]
, 2010 The construction of adaptive nonparametric procedures by means of wavelet thresholding techniques is now a classical topic in modern mathematical statistics.
Durastanti, Claudio +2 more
core
Empirical Research in Statistics Education
, 2016 In this ICME-13 Topical Survey, we provide a review of recent research into statistics education. We focus our review on empirical research that has been published in established educational journals or the proceedings of important conferences that ...
Andreas Eichler, Lucía Zapata‐Cardona
semanticscholar +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Surveying Persons with Disabilities: A Source Guide (Version 1) [PDF]
, 2006 As a collaborator with the Cornell Rehabilitation Research and Training Center on Disability Demographics and Statistics, Mathematica Policy Research, Inc. has been working on a project that identifies the strengths and limitations in existing disability
Bleeker, Martha +2 more
core +1 more source
Experience and Availability of Pelvic Binders at Swedish Trauma Units; A Nationwide Survey [PDF]
Bulletin of Emergency and Trauma, 2018 Objective: To assess availability, experience, and knowledge about the Pelvic Circumferential Compression Device (PCCD) in Sweden.Methods: A telephone interview with the current on-call trauma doctors at all trauma units in Sweden was conducted.
Peyman Bakhshayesh +3 more
doaj
Optimal reinsurance designs based on risk measures: a review
Statistical Theory and Related Fields, 2020 Reinsurance is an effective way for an insurance company to control its risk. How to design an optimal reinsurance contract is not only a key topic in actuarial science, but also an interesting research question in mathematics and statistics.
Jun Cai, Yichun Chi
doaj +1 more source
Software for Spatial Statistics
, 2015 We give an overview of the papers published in this special issue on spatial statistics, of the Journal of Statistical Software. 21 papers address issues covering visualization (micromaps, links to Google Maps or Google Earth), point pattern analysis ...
E. Pebesma, R. Bivand, P. J. Ribeiro
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
What is the value of official statistics and how do we communicate that value? [PDF]
Revista Română de Statistică, 2014 Einstein’s aphorism mentioned above wasn’t meant to colour the text, but we particularly believe it corresponds, in a way, to the topic we plan to introduce during the seminar.
Tudorel ANDREI +2 more
doaj