Results 41 to 50 of about 166,066,358 (299)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Rates of convergence of powered order statistics from general error distribution
Statistical Theory and Related Fields, 2023 Let $ \{X_{n}: n\ge 1\} $ be a sequence of independent random variables with common general error distribution $ \hbox{GED} (v) $ with shape parameter v>0, and let $ M_{n,r} $ denote the r-th largest order statistics of $ X_{1}, X_{2}, \ldots, X_{n ...
Yuhan Zou, Yingyin Lu, Zuoxiang Peng
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Photon statistics on the extreme entanglement [PDF]
Scientific Reports, 2016 AbstractThe effects of photon bunching and antibunching correspond to the classical and quantum features of the electromagnetic field, respectively. No direct evidence suggests whether these effects can be potentially related to quantum entanglement.
Yang Zhang, Jun Zhang, Chang-shui Yu
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Extreme dry and wet events in Iceland: Observations, simulations and scenarios
Meteorologische Zeitschrift, 2007 Monthly extremes of dryness and wetness in Iceland are analysed based on the standardised precipitation index (SPI). The analysis is performed for observations and four sets of coupled atmosphere-ocean climate model simulations (ECHAM5/MPI-OM) to link ...
Frank Sienz +3 more
doaj +1 more source
Local impact analysis of climate change on precipitation extremes: are high-resolution climate models needed for realistic simulations? [PDF]
Hydrology and Earth System Sciences, 2016 This study explores whether climate models with higher spatial resolutions provide higher accuracy for precipitation simulations and/or different climate change signals.
H. Tabari +8 more
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
WEATHER AND CLIMATE EXTREMES IN LIGHT OF THE IPCC SREX (2011) AND BEYOND [PDF]
Aerul şi Apa: Componente ale Mediului, 2012 Weather and climate extremes in light of the IPCC SREX (2011) and beyond. The recent IPCC Special Report (IPCC SREX, 2011) provides a comprehensive overview of meteorological (i.e. weather and climate) extremes and their various aspects.
JÁNOS MIKA
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