Results 61 to 70 of about 166,066,358 (299)
Statistics for Extreme Sea Currents
Journal of the Royal Statistical Society Series C: Applied Statistics, 1997 SUMMARY Estimates of various characteristics of extreme sea currents, such as speeds and their directions, are required when designing offshore structures. This paper extends standard statistical methods for extreme values to handle the directionality, temporal dependence and tidal non-stationarity that are present in sea current ...
Robinson, M. E., Tawn, J. A.
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Near-Extreme Statistics of Brownian Motion [PDF]
Physical Review Letters, 2013 We study the statistics of near-extreme events of Brownian motion (BM) on the time interval [0,t]. We focus on the density of states (DOS) near the maximum ρ(r,t) which is the amount of time spent by the process at a distance r from the maximum. We develop a path integral approach to study functionals of the maximum of BM, which allows us to study the ...
Perret, Anthony +3 more
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FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Inferences on weather extremes and weather-related disasters: a review of statistical methods [PDF]
Climate of the Past, 2012 The study of weather extremes and their impacts, such as weather-related disasters, plays an important role in research of climate change. Due to the great societal consequences of extremes – historically, now and in the future – the ...
H. Visser, A. C. Petersen
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IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Journal of Advances in Modeling Earth SystemsWe present an application of quantile generalized additive models (QGAMs) to study spatially compounding climate extremes, namely extremes that occur (near‐) simultaneously in geographically remote regions. We take as an example wintertime cold spells in
Leonardo Olivetti +2 more
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Advances in Meteorology, 2018 Fifteen temperature indices recommended by the ETCCDI (Expert Team on Climate Change Detection and Indices) were applied to evaluate spatiotemporal variability and trends in annual intensity, frequency, and duration of extreme temperature statistics in ...
Masoud Irannezhad +2 more
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Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Statistique des extrêmes dans les bassins faiblement jaugés : application d'un modèle global pluie-débit à cinq bassins versants en région wallonne (Belgique) [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2008 Statistics of extremes in poorly gauged basins: application of a lumped rainfall-runoff model in five catchments area in Walloon region (Belgium). The RS-PDM© model generates flows in time series on the basis of observed rainfall after self-calibration ...
Debauche O. +3 more
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