Results 81 to 90 of about 166,066,358 (299)

Nonstationary Extremes and the US Business Cycle [PDF]

open access: yes
Considerable attention has been devoted to the statistical analysis of extreme events. Classical peaks over threshold methods are a popular modelling strategy for extreme value statistics of stationary data.
António Rua   +2 more
core  

Linking physical climate risk with mandatory business risk disclosure requirements

open access: yesEnvironmental Research Letters
Mandatory disclosure of physical climate risks to businesses is planned or being implemented in many countries. This raises the question, how viable is it to link increasing physical climate risk, expressed as extreme events, to an individual business ...
A J Pitman   +5 more
doaj   +1 more source

Statistical Inference Using Extreme Order Statistics

open access: yesThe Annals of Statistics, 1975
A method is presented for making statistical inferences about the upper tail of a distribution function. It is useful for estimating the probabilities of future extremely large observations. The method is applicable if the underlying distribution function satisfies a condition which holds for all common continuous distribution functions.
openaire   +2 more sources

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Simulating sub-hourly rainfall data for current and future periods using two statistical disaggregation models: case studies from Germany and South Korea [PDF]

open access: yesHydrology and Earth System Sciences
The simulation of fast-reacting hydrological systems often requires sub-hourly precipitation data to develop appropriate climate adaptation strategies and tools, i.e. upgrading drainage systems and reducing flood risks. However, these sub-hourly data are
I. Vorobevskii   +4 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino   +25 more
wiley   +1 more source

Asymptotics of the extremal excedance set statistic

open access: yesEuropean Journal of Combinatorics, 2015
Answering a question of Clark and Ehrenborg (2010), we determine asymptotics for the number of permutations of size n that admit the most common excedance set. In fact, we provide a more general bivariate asymptotic using the multivariate asymptotic methods of R. Pemantle and M. C. Wilson. We also consider two applications of our main result. First, we
Rodrigo Ferraz de Andrade   +2 more
openaire   +2 more sources

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