Results 131 to 140 of about 1,727,830 (339)

Aviation Forecasting in ICAO [PDF]

open access: yes, 1972
Opinions or plans of qualified experts in the field are used for forecasting future requirements for air navigational facilities and services of international civil aviation. ICAO periodically collects information from Stators and operates on anticipated
Mcmahon, J.
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Cold-air performance of compressor-drive turbine of Department of Energy upgraded automobile gas turbine engine. 1: Volute-manifold and stator performance [PDF]

open access: yes
The aerodynamic performance of the inlet manifold and stator assembly of the compressor drive turbine was experimentally determined with cold air as the working fluid.
Haas, J. E., Roelke, R. J.
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure [PDF]

open access: diamond, 2015
Imran Shah   +13 more
openalex   +1 more source

Programs for calculating quasi-three-dimensional flow in a turbomachine blade row [PDF]

open access: yes
MERIDL is a program that calculates a meridional plane stream function solution, and TSONIC is a program that calculates a blade to blade stream function solution for turbomachine blade passages.
Katsanis, T.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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