Results 161 to 170 of about 1,727,830 (339)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The diverse chemical mixing state of aerosol particles in the southeastern United States

, 2018
Amy L. Bondy, Daniel Bonanno, Ryan C. Moffet, Bingbing Wang, Alexander Laskin, Andrew P. Ault   +5 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A Phasor-Data-Based State Estimator Incorporating Phase Bias Correction

, 2010
Luigi Vanfretti, Joe H. Chow, Sanjoy Sarawgi, Behruz Fardanesh   +3 more
openalex   +2 more sources

Phenotypic Identification of Citrobacter Isolates from Cloacal Swabs of Apparently Healthy Turtles at the River Banks in Lokoja, Kogi State, Nigeria

, 2022
Madubuike Stella Anelechi, Mailafia Samuel Egwu O. Godwin, Olabode H. Olatunde, Momoh A.Habiba, Ode O. Julius, Ramon-Yusuf S.Babatunde   +5 more
openalex   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Fan noise reduction achieved by removing tip flow irregularities behind the rotor - forward arc test configurations [PDF]

The noise source caused by the interaction of the rotor tip flow irregularities (vortices and velocity defects) with the downstream stator vanes was studied. Fan flow was removed behind a 0.508 meter (20 in.) diameter model turbofan through an outer wall
Dittmar, J. H., Mackinnon, M. J., Woodward, R. P.   +2 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Two-Phase Fluid Simulation Using a Diffuse Interface Model with Peng--Robinson Equation of State

, 2014
Zhonghua Qiao, Shuyu Sun
openalex   +2 more sources