Results 111 to 120 of about 8,442,055 (315)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Brief to Ontario Cabinet, re: economic situation of Ontario Women

open access: yes
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women
core  

B1976-1 Concern re Sub-contracting Expressed to Minister of Government Services

open access: yes, 1976
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

STATUS KESEHATAN IBU HAMIL DAN MORBIDITAS ANAK DI KABUPATEN SUKABUMI TAHUN 2006

open access: yes, 2016
Indicators size from mother's alive continuance and child in general accept as indicator ismother's mortality rate (MMR), Child mortaiity rate (CMR) in belong baby/infant mortality rate (IMR).The important get indicator from accumulator use and AKB as ...
Senewe, Felly Philipus; Puslitbang Ekologi & Status Kesehatan   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Brief to the Government of Ontario

open access: yes, 1972
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women
core  

STATUS KESEHATAN MASYARAKAT DAN FAKTOR-FAKTOR YANG BERHUBUNGAN DI NANGGROE ACEH DARUSSALAM

open access: yes, 2012
This study describes community health status in NAD Province after tsunami disaster and its relatedfactors. Health status was obtained from data of "Surkesda NAD 2006" which included questions ofphysical and mental health of respondents aged 15 years in ...
H., Puti Sari; Puslitbang Ekologi dan Status Kesehatan   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Brief to the Board of Education of Metropolitan Toronto

open access: yes
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women
core  

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