Results 81 to 90 of about 14,914,334 (297)

Baikal-GVD: status and prospects

, 2018
Baikal-GVD is a next generation, kilometer-scale neutrino telescope under construction in Lake Baikal. It is designed to detect astrophysical neutrino fluxes at energies from a few TeV up to 100 PeV.
:, Avrorin, A. D., Avrorin, A. V., Aynutdinov, V. M., Bannash, R., Belolaptikov, I. A., Brudanin, V. B., Budnev, N. M., Collaboration, Baikal-GVD, Domogatsky, G. V., Doroshenko, A. A., Dvornický, R., Dyachok, A. N., Dzhilkibaev, Zh. -A. M., Fajt, L., Fialkovsky, S. V., Gafarov, A. R., Golubkov, K. V., Gres, T. I., Honz, Z., Kebkal, K. G., Kebkal, O. G., Khramov, E. V., Kolbin, M. M., Konischev, K. V., Korobchenko, A. P., Koshechkin, A. P., Kozhin, V. A., Kulepov, V. F., Kuleshov, D. A., Milenin, M. B., Mirgazov, R. A., Osipova, E. R., Pan'kov, L. V., Panfilov, A. I., Petukhov, D. P., Pliskovsky, E. N., Rjabov, E. V., Rozanov, M. I., Rushay, V. D., Safronov, G. B., Shelepov, M. D., Shoibonov, B. A., Shtekl, I., Simkovic, F., Solovjev, A. G., Sorokovikov, M. N., Suvorova, O. V., Tabolenko, V. A., Tarashansky, B. A., Yakovlev, S. A., Zagorodnikov, A. V., Zurbanov, V. L.   +52 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Glycemic index of some protein-free food products for individuals with non-dialysis-dependent chronic kidney disease

Nutrition & Metabolism
Background Chronic kidney disease (CKD) is a major public health issue and the third leading cause of death globally. In the conservative phase of CKD, a low-protein diet is recommended to slow disease progression, and protein-free products are commonly ...
Alessandro Leone, Francesca Menichetti, Franca Criscuoli, Giovanni Fiorillo, Stefano Ravasenghi, Maria Cristina Casiraghi, Simona Bertoli   +6 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Relationship between bmi and glomerular filtration rate in a large cohort initiating a weight loss program: differential contributions of fat mass, fat-free mass, and abdominal fat compartments

Nutrition Journal
Background The relationship between BMI and chronic kidney disease is controversial, likely due to the inability of BMI to accurately define body composition and adipose tissue distribution.
Alessandro Leone, Francesca Menichetti, Laila Vignati, Federica Sileo, Ramona De Amicis, Andrea Foppiani, Simona Bertoli, Alberto Battezzati   +7 more
doaj   +1 more source

Stakeholder perspectives on integrating Ayurveda and Indian Indigenous Knowledge Systems into higher education: An exploratory study

Social Sciences and Humanities Open
The renewed emphasis on mainstreaming Indigenous Knowledge Systems (IKS) in higher education globally, including in India, has sparked interest in leveraging traditional teaching methodologies for holistic learner development.
Panchali Moitra, Jagmeet Madan
doaj   +1 more source

Epidemiology of Schistosomiasis in the People’s Republic of China, 2004

Emerging Infectious Diseases, 2007
Results from the third nationwide cluster sampling survey on the epidemiology of schistosomiasis in the People’s Republic of China, conducted by the Ministry of Health in 2004, are presented.
Xiao-Nong Zhou, Jia-Gang Guo, Xiao-Hua Wu, Qing-Wu Jiang, Jiang Zheng, Hui Dang, Xian-Hong Wang, Jing Xu, Hong-Qing Zhu, Guan-Ling Wu, Yue-Sheng Li, Xing-Jian Xu, Hong-Gen Chen, Tian-Ping Wang, Yin-Chang Zhu, Dong-Chuan Qiu, Xing-Qi Dong, Gen-Ming Zhao, Shao-Ji Zhang, Nai-Qing Zhao, Gang Xia, Li-Ying Wang, Shi-Qing Zhang, Dan-Dan Lin, Ming-Gang Chen, Yang Hao   +25 more
doaj   +1 more source

From Opportunity to Status [PDF]

, 1976
[Excerpt] When Ronald Knox, at the age of four, was asked what he did for his insomnia, he replied, I lie awake and think about the past. I suspect that even the future celebrated biblical scholar did not, at the age of four, have much of a past to ...
Konvitz, Milton R
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Factors predicting trust between GPs and OPs

International Journal of Integrated Care, 2001
Purpose: To study possible differences in trust between general practitioners (GPs) and occupational physicians (OPs) and the explanatory factors for trust. Insight into the factors predicting trust can improve programmes for stimulating the co-operation
A.P. Nauta, J. von Grumbkow
doaj   +1 more source