Results 201 to 210 of about 64,777 (300)

MiR‐30a‐5p mediates epileptogenesis in epilepsy models by targeting SOX4 to regulate the Wnt/β‐catenin pathway

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The pathogenesis of epilepsy is closely associated with neuronal synaptic plasticity. MicroRNAs (miRNAs) can regulate various biological processes by binding to specific sequences on target genes. This study employs bioinformatics, molecular dynamics, and experimental approaches to investigate the mechanism by which MiR‐30a‐5p treats
Zhenlin Yang   +4 more
wiley   +1 more source

Trends in antiseizure medication monotherapy for pediatric epilepsy in the United States

open access: yesEpilepsia Open, EarlyView.
Abstract Objective National prescribing trends for antiseizure medication (ASM) in children with epilepsy over the past decade are unclear. Despite the 2021 SANAD II trials supporting lamotrigine and valproate for focal and generalized epilepsies, respectively, it is unknown if their use increased.
Adam P. Ostendorf   +6 more
wiley   +1 more source

Postmortem MRI reveals distinct structural features in sudden unexpected death in epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Magnetic resonance imaging (MRI) abnormalities have been reported in individuals who later die from sudden unexpected death in epilepsy (SUDEP), but their specificity and predictive value remain uncertain. Postmortem MRI (PM‐MRI) offers a unique opportunity to distinguish structural features associated with SUDEP from changes related to ...
Andrea Hill   +9 more
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine-induced status epilepticus. [PDF]

open access: yesEpilepsia
Sun C   +6 more
europepmc   +1 more source

Long‐Term Outcomes of Patients Undergoing Cricothyrotomy at a Tertiary Care Level One Trauma Center

open access: yesThe Laryngoscope, EarlyView.
This retrospective study of 48 patients undergoing emergent cricothyrotomy (2014–2025) evaluated short‐ and long‐term outcomes and complications. Common complications included dysphagia, pneumonia, and dysphonia, with delayed conversion to tracheostomy associated with increased pneumonia risk; long‐term issues included persistent dysphagia, subglottic ...
Shivani Raizada   +6 more
wiley   +1 more source

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