Results 31 to 40 of about 3,079,576 (204)

Plasticity of GABAB receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus [PDF]

, 2003
Several neurotransmitters, including GABA acting at presynaptic GABAB receptors, modulate glutamate release at synapses between hippocampal mossy fibers and CA3 pyramidal neurons.
Bowery, N.G., Walker, M.C., Chandler, K.E., Chandler, K. E., Princivalle, A.P., Walker, M. C., Princivalle, A. P., Fabian-Fine, R., Bowery, N. G., Kullmann, D. M., Kullmann, D.M.   +10 more
core  

Super-Refractory Status Epilepticus: An Atypical Presentation and Case-Based Review

, 2015
Super-refractory status epilepticus is known to typically arise either from a distinct underlying cause or, in patients with no history of epilepsy, from no overt cause.
Olusegun OYEWOLE, Fola A. FAPONLE, Chiazor Udochukwu ONYIA, Ayo M. ADEBIYI, Morenikeji A. KOMOLAFE   +4 more
core   +1 more source

Super-Refractory Status Epilepticus Treated with High Dose Perampanel: Case Series and Review of the Literature

Case Reports in Critical Care, 2019
Introduction. Acute symptomatic seizures are frequent in the critically ill patient and can be difficult to treat. The novel anticonvulsant perampanel may be effective in the treatment of status epilepticus considering its mechanism of action of being an
Christopher R. Newey, Naresh Mullaguri, Stephen Hantus, Vineet Punia, Pravin George   +4 more
doaj   +1 more source

Predictors of high functional disability and mortality at 3 months in patients with status epilepticus

eNeurologicalSci, 2022
Purpose: There are differences in epidemiology, etiology, and outcome in status epilepticus (SE) between developing and developed countries, which limits generalizability. We evaluated factors related to outcome at 3 months in SE patients in a developing
Dannys Rivero Rodríguez, Graham Pluck
doaj   +1 more source

Ofatumumab Therapy and Long‐Term Seizure Outcomes of Patients With Relapsing Anti‐NMDA Receptor Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley   +1 more source

Withdrawal of parenteral phenobarbitone - Implications for resource-poor countries [PDF]

, 2005
Parenteral phenobarbitone is an integral part of the management of status epilepticus, especially in the context of resource-poor countries. It is highly effective at controlling seizures.
Wilmshurst, JM, van Toorn, R, Newton, Charles, Newton, CRJC, Wilmshurst, J. M., Newton, C. R. J. C., Newton, CR, Van Toorn, R.   +7 more
core  

Status Epilepticus in the Emergency Department

Journal of Education and Teaching in Emergency Medicine, 2017
Audience: This simulation can be used for EM learners of any level including medical students, junior residents and senior residents. Introduction: Seizures are the result of abnormal or disorganized cortical electrical activity in the brain. Status
Jonathan Lee, Alisa Wray
doaj   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Super Refractory Status Epilepticus in Neuropsychiatric Systemic Lupus Erythematosus: A Rare Case

, 2019
Systemic lupus erythematosus (SLE) is an autoimmune disease with extensive organ involvement. Neuropsychiatric-SLE (NP-SLE) includes the involvement of the central nervous system, and has an epileptic seizure rate of 6.7% to 14.4%.
Mehmet Fatih YETKİN, Elif Gülşen KÖSE, KÖSE, Elif Gülşen, Mehmet Fatih GÖL, YETKİN, Mehmet Fatih, GÖL, Mehmet Fatih, ERDOĞAN, Füsun Ferda, Füsun Ferda ERDOĞAN   +7 more
core   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source