Results 61 to 70 of about 32,338 (260)

Clinical outcomes of intravenous levetiracetam treatment in patients with renal impairment

Neurology International, 2018
Intravenous levetiracetam has been approved for use as an antiepileptic drug, as well as in cases of status epilepticus. There are few reports that detail the clinical data and outcomes associated with this antiepileptic drug, particularly in patients ...
Anyamanee Lapmag, Sunee Lertsinudom, Aporanee Chaiyakam, Kittisak Sawanyawisuth, Somsak Tiamkao   +4 more
doaj   +1 more source

Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus

Frontiers in Neuroscience, 2020
Repetitive or prolonged seizures (status epilepticus) can damage neurons within the hippocampus, trigger gliosis, and generate an enduring state of hyperexcitability.
Aasia Batool, Thomas D. M. Hill, Thomas D. M. Hill, Ngoc T. Nguyen, Ngoc T. Nguyen, Elena Langa, Elena Langa, Mairéad Diviney, Catherine Mooney, Catherine Mooney, Gary P. Brennan, Gary P. Brennan, Niamh M. C. Connolly, Amaya Sanz-Rodriguez, Amaya Sanz-Rodriguez, Brenton L. Cavanagh, David C. Henshall, David C. Henshall   +17 more
doaj   +1 more source

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

Epileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini, Evripidis Pityrigkas, Eleni Liouta, Georgia Pepe, Vasiliki Poulidou, Martha Spilioti, Vasilios K. Kimiskidis   +6 more
wiley   +1 more source

Evolution of Cerebral Atrophy in a Patient with Super Refractory Status Epilepticus Treated with Barbiturate Coma

Case Reports in Neurological Medicine, 2017
Introduction. Status epilepticus is associated with neuronal breakdown. Radiological sequelae of status epilepticus include diffusion weighted abnormalities and T2/FLAIR cortical hyperintensities corresponding to the epileptogenic cortex.
Christopher R. Newey, Pravin George, Premkumar Nattanmai, Christine Ahrens, Stephen Hantus, Aarti Sarwal   +5 more
doaj   +1 more source

Analysis of Fulminant Cerebral Edema in Acute Pediatric Encephalitis

Pediatrics and Neonatology, 2016
Acute pediatric encephalitis with fulminant cerebral edema can rapidly become fatal or result in devastating neurological sequelae. Methods: All cases coded with the discharge diagnosis of acute encephalitis between January 2000 and December 2010 were ...
Shih-Yun Lan, Jainn-Jim Lin, Shao-Hsuan Hsia, Huei-Shyong Wang, Cheng-Hsun Chiu, Kuang-Lin Lin   +5 more
doaj   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

New-Onset Refractory Status Epilepticus Secondary to COVID-19 Infection in Adults: A Systematic Review

Neuropsychiatric Disease and Treatment, 2022
Aabiya Arif,1 Yeny Chavarria,2 Mohammad Aadil Qamar,1 Sameer Saleem Tebha,3 Mehwish Butt,3 Khulud Qamar,4 Abubakr Yosufi5 1Medical School, Ziauddin University, Karachi, Sindh, Pakistan; 2Department of Neurology, University of California, Irvine, CA, USA;
Arif A, Chavarria Y, Qamar MA, Tebha SS, Butt M, Qamar K, Yosufi A   +6 more
doaj  

Levetiracetam as an alternative to phenytoin for second-line emergency treatment of children with convulsive status epilepticus: the EcLiPSE RCT

Health Technology Assessment, 2020
Background: Convulsive status epilepticus is the most common neurological emergency in children. Its management is important to avoid or minimise neurological morbidity and death.
Richard E Appleton, Naomi EA Rainford, Carrol Gamble, Shrouk Messahel, Amy Humphreys, Helen Hickey, Kerry Woolfall, Louise Roper, Joanne Noblet, Elizabeth Lee, Sarah Potter, Paul Tate, Nadia Al Najjar, Anand Iyer, Vicki Evans, Mark D Lyttle   +15 more
doaj   +1 more source

Can epilepsy be predicted after the first febrile seizure? Insights from machine learning of postictal EEG

Epileptic Disorders, EarlyView.
Abstract Objective Febrile seizures (FS) are the most common seizures in childhood, yet identifying children at risk of developing epilepsy after the first FS remains challenging. We aimed to evaluate the prognostic potential of machine learning (ML) algorithms applied to post‐febrile seizure electroencephalography (EEG) recordings.
Boran Şekeroğlu, Hüseyin Öztoprak, Özlem Yayıcı Köken, Hatice Demir, Mehpare Sarı Yanartaş, Deniz Yılmaz, Burçin Şanlıdağ, Ayşegül Neşe Çıtak Kurt   +7 more
wiley   +1 more source

Gut microbiota shifts and short‐chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet

Epileptic Disorders, EarlyView.
Abstract Objective The olive oil–based Mediterranean ketogenic diet (MedKD) may support patients with drug‐resistant epilepsy (DRE) or neurometabolic disorders by integrating ketogenic therapy with the cardiometabolic and neuroprotective advantages of the Mediterranean diet.
Sofia Zouganeli, Evdokia K. Mitsou, Mary Yannakoulia, Evangelia Intze, Konstantinos C. Mountzouris, Smaragdi Fessatou, Achilleas Attilakos, Adamantini Kyriacou, Argyrios Dinopoulos   +8 more
wiley   +1 more source