Results 81 to 90 of about 10,893,049 (312)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Gibbs phenomenon and the emergence of the steady-state in quantum transport

, 2019
Simulations are increasingly employing explicit reservoirs - internal, finite regions - to drive electronic or particle transport. This naturally occurs in simulations of transport via ultracold atomic gases.
Zwolak, Michael
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Inconsistencies in steady-state thermodynamics [PDF]

Physical Review E, 2014
We address the issue of extending thermodynamics to nonequilibrium steady states. Using driven stochastic lattice gases, we ask whether consistent definitions of an effective chemical potential mu, and an effective temperature T_e, are possible. mu and T_e are determined via coexistence, i.e., zero flux of particles and energy between the driven system
Dickman, Ronald, Motai, Ricardo
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Steady state entanglement of two coupled qubits

, 2010
The maximum entanglement between two coupled qubits in the steady state under two independent incoherent sources of excitation is reported. Asymmetric configurations where one qubit is excited while the other one dissipates the excitation are optimal for
An, Angelakis, Ashhab, Bayer, Benatti, Benatti, Benson, Bloch, Braun, Briegel, Campbell, Clark, Clarke, Contreras-Pulido, del Valle, del Valle, del Valle, Elena del Valle, Ficek, Ficek, Gallardo, Gerardot, Hao, Hartmann, Hartmann, Hor-Meyll, Horodecki, Huang, Huelga, Imamoglu, Jakóbczyk, Jakóbczyk, Kim, Krenner, Ladd, Lambert, Laucht, Laussy, Li, Majer, Munro, Osnaghi, Plenio, Rivas, Schneider, Shan, Steffen, Verstraete, Wang, Wootters, Xiang-Ping, Xu, Yi, Yu, Zheng, Zhou   +55 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Моделювання електричних параметрів газорозрядної лампи високого тиску

Elektrotehnìka ta Elektroenergetika, 2010
Запропоновано модель електричних параметрів газорозрядної лампи високого тискуз урахуванням нелінійної вольт-амперної характеристики та її структурно-логічну схему. Наведено результати моделювання та експериментальні дослідження.
D. A. Konchukovskiy
doaj   +1 more source

Autonomous quantum thermal machine for generating steady-state entanglement [PDF]

, 2015
We discuss a simple quantum thermal machine for the generation of steady-state entanglement between two interacting qubits. The machine is autonomous in the sense that it uses only incoherent interactions with thermal baths, but no source of coherence or
Jonatan Bohr Brask, G. Haack, N. Brunner, M. Huber   +3 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source