Results 51 to 60 of about 418,709 (308)

Steady-state performance analysis and modelling of directly driven interior permanent magnet wind generators

open access: yes, 2011
Steady-state performance analysis and modelling of directly driven interior permanent magnet wind ...
SA Saleh (17322085)   +2 more
core   +1 more source

Velocity of detonation measurement and fragmentation analysis to evaluate blasting efficacy

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2018
In holes, the measurement of the velocity of detonation (VOD) helps in comparing and evaluating relative performance of explosives. In this paper a blast performance assessment was conducted based on the results obtained from the steady state VOD ...
Eugie Kabwe
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Periodic steady-state analysis augmented with design equality constraints

open access: yes, 2008
A design-oriented periodic steady-state analysis is presented in this paper. The new analysis nds the values of circuit parameters that result in a desired circuit performance specied by a set of equality constraints. This is done by including the design
Kartikeya Mayaram   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A comparison study of canonical correlation analysis based methods for detecting steady-state visual evoked potentials

open access: yes, 2015
Canonical correlation analysis (CCA) has been widely used in the detection of the steady-state visual evoked potentials (SSVEPs) in brain-computer interfaces (BCIs).
Yijun Wang   +11 more
core   +1 more source

A self-validating control system based approach to plant fault detection and diagnosis [PDF]

open access: yes, 2001
An approach is proposed in which fault detection and diagnosis (FDD) tasks are distributed to separate FDD modules associated with each control system located throughout a plant.
Chen, J., Howell, J.
core   +1 more source

Associations Between Types of Balance Performance in Healthy Individuals Across the Lifespan: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Physiology, 2018
Background: The objective of this systematic review and meta-analysis was to quantify and statistically compare correlations between types of balance performance in healthy individuals across the lifespan.Methods: Literature search was performed in the ...
Rainer Kiss   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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