Results 81 to 90 of about 418,709 (308)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Simulation-Based Analysis of DRL Exploitation Rate for Voltage and Frequency Stability in a Single-Inverter Microgrid Control System

IEEE Access
This paper discusses the development and performance evaluation of a single-inverter-based microgrid control system using a Deep Reinforcement Learning (DRL) agent trained with the Twin Delayed Deep Deterministic Policy Gradient (TD3) algorithm.
Noer Fadzri Perdana Dinata, Makbul Anwari Muhammad Ramli, Muhammad Irfan Jambak, Prisma Megantoro, Muhammad Abu Bakar Sidik   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Steady-state average run length(s)

, 2021
The average run length (ARL), with its various phenotypes, is the prevailing performance measure for evaluating control charts, or change-point detection schemes.
Knoth, Sven
core   +1 more source

Performance Evaluation of ASAP3 for Steady-state Output Analysis [PDF]

Proceedings of the Winter Simulation Conference, 2005., 2006
Natalie M. Steiger, Emily K. Lada, James R. Wilson   +2 more
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Comparison Of Quasi-Steady State And Dynamic Simulation Approaches For The Calculation Of Building Energy Needs: Thermal Losses

, 2012
One of the aims of the European Directive 2010/31/EU (formerly 2002/91/EC) is to reduce the energy consumption of buildings introducing an energy labeling protocol which is expected to capture the attention and reorient the market, sustaining the ...
Gasparella, Andrea, Pernigotto, Giovanni
core  

Dynamic and steady-state performance analysis for multi-state repairable reconfigurable manufacturing systems with buffers

, 2020
Reconfigurable manufacturing systems (RMSs) are considered the solution of choice when variable production capacity and functionality are required. A combinational approach, which integrates the steady-state probabilities of repairable reconfigurable ...
Zhang, Yanjun,, Pan, Ruilin,, Cai, Jing,, Zhang, Yongjin,, Zhao, Ming,   +4 more
core   +1 more source

An Energy Analysis in Transient Pool Boiling Experiments at Short Durations [PDF]

AUT Journal of Mechanical Engineering
In this investigation, the performance of coolant in various operating conditions was examined through an energy analysis of experimental data. A novel method was introduced for presenting pool boiling test results, facilitating coolant performance ...
Ahmadreza Ayoobi, Abbas Afshari, Mohammd Farmani   +2 more
doaj   +1 more source