Results 71 to 80 of about 2,680,718 (334)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The steady-states of splitter networks
CoRRWe introduce splitter networks, which abstract the behavior of conveyor belts found in the video game Factorio. Based on this definition, we show how to compute the steady-state of a splitter network. Then, leveraging insights from the players community, we provide multiple designs of splitter networks capable of load-balancing among several conveyor ...
Couëtoux, Basile +2 more
openaire +4 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Analysis of Steady-state Characteristics of Thermal Subsystem in Integrated Energy System
发电技术, 2020 The integrated energy system (IES) includes various energy forms, complex operation modes, abundant control equipment and coupling links, which brings challenges to its steady-state modeling and steady-state power flow calculation. In order to obtain the
Lu QU +4 more
doaj +1 more source
, 2015 We follow the evolution of an asymptotically AdS black brane with a fixed temperature gradient at spatial infinity until a steady state is formed. The resulting energy density and energy flux of the steady state in the boundary theory are compared to a ...
Amado, Irene, Yarom, Amos
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Heliyon, 2018 The efficiency by which animals utilize dietary energy is fundamental to the cost of production for protein of animal origin and to the carbon footprint an animal industry has.
A.L. Schaefer +11 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Steady-state creep in the mantle
Annals of Geophysics, 1977 SUMMARY - The creep equations for steady-state flow of olivine at high<br />pressure and temperature are compared in an attempt to elucidate the rheological<br />behaviour of the mantle.
G. RANALLI
doaj +1 more source