Results 71 to 80 of about 18,641,062 (303)

The steady-states of splitter networks

open access: yesCoRR
We introduce splitter networks, which abstract the behavior of conveyor belts found in the video game Factorio. Based on this definition, we show how to compute the steady-state of a splitter network. Then, leveraging insights from the players community, we provide multiple designs of splitter networks capable of load-balancing among several conveyor ...
Couëtoux, Basile   +2 more
openaire   +5 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Steady-state kinetic parameters of recombinant TsTPI and SmTPI in comparison to HsTPI.

open access: yes, 2020
Steady-state kinetic parameters of recombinant TsTPI and SmTPI in comparison to HsTPI.
Pedro Jimenez-Sandoval (831603)   +7 more
core   +1 more source

Steady-State Creep of Asphalt Concrete

open access: yesApplied Sciences, 2017
This paper reports the experimental investigation of the steady-state creep process for fine-grained asphalt concrete at a temperature of 20 ± 2 °С and under stress from 0.055 to 0.311 MPa under direct tension and was found to occur at a constant rate ...
Alibai Iskakbayev   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Steady-state kinetic parameters of OTC and its variants with respect to ornithine.

open access: yes, 2020
Steady-state kinetic parameters of OTC and its variants with respect to ornithine.
Kevin E. Ramos (8415567)   +8 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Steady-state solution of a fully coupled system in the limit of large D.

open access: yes, 2016
As in Fig 2, the near steady-state solution of a fully coupled system was obtained by VCell hybrid for the fast-diffusion limit and validated against Gibson-Bruck stochastic nonspatial solver. Results from each solver are based on 20,000 realizations and
Fei Gao (29262)   +4 more
core   +1 more source

Quasi-steady-state air waveguide

open access: yes, 2023
We report the first generation of quasi-steady-state air waveguides capable of guiding high average power laser beams. The guides are produced by high-repetition rate patterned filamentation of femtosecond laser pulses.
A. Tartaro (14417898)   +2 more
core   +1 more source

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