Results 201 to 210 of about 125,716 (297)

Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

The Lancet, 2015
B. Neuschwander‐Tetri, R. Loomba, A. Sanyal, J. Lavine, M. L. Natta, M. Abdelmalek, N. Chalasani, S. Dasarathy, A. Diehl, B. Hameed, K. Kowdley, A. McCullough, N. Terrault, J. Clark, J. Tonascia, E. Brunt, D. Kleiner, E. Doo   +17 more
semanticscholar   +1 more source

Hepatic fibrosis in patients diagnosed with rheumatoid arthritis and psoriatic arthritis receiving methotrexate: A cross‐sectional analysis using transient elastography

Rheumatology &Autoimmunity, EarlyView.
Hepatic fibrosis and metabolic syndrome are more prevalent in PsA patients treated with methotrexate, compared to RA patients. Metabolic syndrome is associated with the risk of hepatic fibrosis in patients diagnosed with PsA and RA even after adjustment forcumulative methotrexate exposure.
Ratchaya Lertnawapan, Soonthorn Chonprasertsuk, Sith Siramolpiwat, Kanon Jatuworapruk   +3 more
wiley   +1 more source

Histone lactylation: A key epigenetic modulator in the pathogenesis of metabolic dysfunction-associated steatohepatitis and alcoholic steatohepatitis. [PDF]

World J Hepatol
Singh MM, Shah A, Rajak S, Chaturvedi CP, Sinha RA.   +4 more
europepmc   +1 more source

Effect of angiolin on the functional state of the liver in experimental steatohepatitis

, 2019
K. V. Pivtorak
openalex   +2 more sources

Organic solute transporter OSTα/β is overexpressed in nonalcoholic steatohepatitis and modulated by drugs associated with liver injury [PDF]

, 2018
Melina M. Malinen, Izna Ali, Jacqueline Bezençon, James J. Beaudoin, Kim L. R. Brouwer   +4 more
openalex   +1 more source

Obstructive sleep apnea and cardiovascular disease in individuals with metabolic dysfunction‐associated fatty liver disease: A prospective cohort study

Sleep Research, EarlyView.
Abstract Objective To assess the association between obstructive sleep apnea (OSA) risk levels and major cardiovascular disease (CVD) subtypes in individuals with metabolic dysfunction‐associated fatty liver disease (MAFLD). Methods This cohort study included 128,022 MAFLD participants from the UK Biobank without CVD at baseline.
Haizhen Chen, Ying Zheng, Hanzhang Wu, Ningjian Wang, Xiao Tan   +4 more
wiley   +1 more source

Metabolic dysfunction-associated steatohepatitis is the leading indication for adult liver transplantation in Saudi Arabia. [PDF]

PLoS One
Alqahtani SA, AlMuhaidib S, Raptis DA, Al-Hamoudi WK, Reddy KR, Broering DC, Alghamdi SA, OTCE Collaborative.   +7 more
europepmc   +1 more source

Sevelamer Improves Steatohepatitis, Inhibits Liver and Intestinal Farnesoid X Receptor (FXR), and Reverses Innate Immune Dysregulation in a Mouse Model of Non-alcoholic Fatty Liver Disease [PDF]

, 2016
Brett McGettigan, Rachel H. McMahan, Yuhuan Luo, Xiaoxin X. Wang, David J. Orlicky, Cara E. Porsche, Moshe Levi, Hugo R. Rosen   +7 more
openalex   +1 more source

Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids.

Cell Metabolism, 2019
Rie Ouchi, Shodai Togo, M. Kimura, T. Shinozawa, Masaru Koido, H. Koike, Wendy L Thompson, Rebekah A. Karns, C. Mayhew, P. McGrath, H. McCauley, Ran-ran Zhang, Kyle Lewis, Shoyo Hakozaki, Autumn Ferguson, Norikazu Saiki, Yosuke Yoneyama, I. Takeuchi, Y. Mabuchi, C. Akazawa, H. Yoshikawa, James M. Wells, T. Takebe   +22 more
semanticscholar   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source