Results 131 to 140 of about 236,526 (353)

Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice [PDF]

, 2005
Aimin Xu, Michael C. Lam, Kok Weng Chan, Yu Wang, Jialiang Zhang, Ruby L.C. Hoo, Jian Xu, Baoying Chen, Wing-Sun Chow, Annette W.K. Tso, Karen S.L. Lam   +10 more
openalex   +1 more source

Validation of steatosis-associated fibrosis estimator (SAFE) in Indian patients with non-alcoholic fatty liver disease [PDF]

, 2022
Nipun Verma, Ajay Duseja, Manu Mehta, Priya Singh, Arka De, Survadeep Mitra, Ashim Das   +6 more
openalex   +1 more source

Ferritin heavy chain Is the host factor responsible for HCV-Induced inhibition of apoB-100 production and is required for efficient viral infection [PDF]

, 2012
Hepatic fat export occurs by apolipoprotein B-100-containing lipoprotein production, whereas impaired production leads to liver steatosis. Hepatitis C virus (HCV) infection is associated to dysregulation of apoB-100 secretion and steatosis; however, the ...
AMICONE, Laura, Claudia Montaldo, Cristina Di Giacomo, Giuseppe Ippolito, Laura Santangelo, Leopoldo Paolo Pucillo, MANCONE, Carmine, Tonino Alonzi, TRIPODI, Marco, Viviana Costa   +9 more
core   +3 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study

Hepatology, EarlyView., 2022
Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef, Milan J. Sonneveld, Maryam Kavousi, M. Arfan Ikram, Robert A. de Man, Robert J. de Knegt   +5 more
wiley   +1 more source

Hepatitis C Virus (HCV) Infection and Hepatic Steatosis

International Journal of Medical Sciences, 2006
There are two discrete forms of steatosis that may be found in patients infected with hepatitis C virus (HCV). Metabolic steatosis can coexist with HCV, regardless of genotype, in patients with risk factors such as obesity, hyperlipidemia, and insulin ...
doaj  

SIV Infection Is Associated with Transient Acute-Phase Steatosis in Hepatocytes In Vivo

Viruses
Metabolic-dysfunction-associated fatty liver disease (MAFLD) is a major cause of morbidity and mortality in HIV-infected individuals, even those receiving optimal antiretroviral therapy.
Nina Derby, Sreya Biswas, Sofiya Yusova, Cristina Luevano-Santos, Maria Cristina Pacheco, Kimberly A. Meyer, Brooke I. Johnson, Miranda Fischer, Katherine A. Fancher, Cole Fisher, Yohannes M. Abraham, Conor J. McMahon, Savannah S. Lutz, Jeremy V. Smedley, Benjamin J. Burwitz, Donald L. Sodora   +15 more
doaj   +1 more source

Reply to: The presence of diabetes impacts liver fibrosis and steatosis by transient elastography in a primary care population

, 2021
Hirsh D. Trivedi, Michael P. Curry, Michelle Lai   +2 more
openalex   +1 more source

Additive effect of non-alcoholic fatty liver disease on metabolic syndrome-related endothelial dysfunction in hypertensive patients [PDF]

, 2016
Metabolic syndrome (MS) is characterized by an increased risk of incident diabetes and cardiovascular (CV) events, identifying insulin resistance (IR) and endothelial dysfunction as key elements.
Caroleo B, Cimellaro A, Maio R, Perticone F, Perticone M, Sciacqua A, Sesti G   +6 more
core   +1 more source

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

Advanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang, Zhan‐Zhan Li, Shu‐Ding Sun, Ya‐Gang Song, Jin‐Xin Miao, Xiang‐Xiang Wu, Yong‐Li Han, Xiao‐Lei Zhang, Wen‐Jing Chen, Qing‐Hua Wang, Yu Zhang, Yiping Fu, Yu‐ting Liu, Lin‐yan Lang, Wen‐Xia Zhao, Ming‐San Miao   +15 more
wiley   +1 more source