Results 131 to 140 of about 141,920 (316)

Connective tissue growth factor, steatosis and fibrosis in patients with chronic hepatitis C

, 2007
BACKGROUND/AIM: Both steatosis and insulin resistance have been linked to accelerated fibrosis in chronic hepatitis C. Connective tissue growth factor (CTGF) plays a major role in extracellular matrix production in fibrotic disorders including cirrhosis,
Carl M. Oneta, Malinverni, Raffaele, Jean-François Dufour, Giacchino Leandro, Raffaele Malinverni, Negro, Francesco, Helbling, Beat, Dufour, Jean-François, Rubbia-Brandt, Laura, Jean-Jacques Gonvers, Francesco Negro, Oneta, Carl M., Leandro, Giacchino, Beat Helbling, null null, Gonvers, Jean-Jacques, Caroline Hora, Beat Muellhaupt, Hora, Caroline, Oneta, Carl M, Muellhaupt, Beat, Laura Rubbia-Brandt   +21 more
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Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

Elevated systemic monocyte chemoattractrant protein-1 in hepatic steatosis without significant hepatic inflammation

, 2011
Non-alcoholic fatty liver disease (NAFLD) is strongly associated with obesity and the metabolic syndrome. It encompasses a clinico-pathologic spectrum of conditions ranging from simple steatosis to nonalcoholic steatohepatitis (NASH). The latter develops
Lukas Moleda, Huber, Hanna, Claus Hellerbrand, Niessen, Catrin, Reiner Wiest, Schacherer, Doris, Georgi Kirovski, Wiest, Reiner, Doris Schacherer, Wobser, Hella, Moleda, Lukas, Buechler, Christa, Dorn, Christoph, Hella Wobser, Catrin Niessen, Hanna Huber, Kirovski, Georgi, Christoph Dorn, Christa Buechler, Hellerbrand, Claus   +19 more
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Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Nonalcoholic liver steatosis

, 2020
Tato práce se zabývá nealkoholickou jaterní steatózou. V první části jsou popsány příčiny a mechanismy vzniku nealkoholické steatózy jater. Dále se práce zabývá spojením mezi nealkoholickou jaterní steatózou a dalšími metabolickými poruchami a mechanismy
Suchý, Jindřich
core  

Imaging of hepatic steatosis and fatty sparing

, 2007
Radiology has gained importance in the non-invasive diagnosis of hepatic steatosis. Ultrasonography is usually the first imaging modality for the evaluation of hepatic steatosis.
KARÇAALTINCABA, MUSTURAY, Akhan, Okan
core   +1 more source

Potential of Bee Pollen as a Nutraceutical And/Or Functional Ingredient for Metabolic Syndrome Management: In Vitro Antioxidant, Anti‐Inflammatory, and Digestive Enzyme Inhibitory Activities

Food Chemistry International, EarlyView.
Bee pollen samples from China and Spain exhibited in vitro antioxidant, anti‐inflammatory, and digestive enzyme inhibitory activities due to their composition, suggesting their potential as a nutraceutical or functional ingredient to help counteract oxidative stress, chronic inflammation, and metabolic disorders.
Adriana Maite Fernández‐Fernández, Victoria Olt, Jessica Báez, Marcelo Miraballes, Melissa Romero, Cecilia Dauber, Ignacio Vieitez, Estela Santos, Adriana Gámbaro, Alejandra Medrano   +9 more
wiley   +1 more source

Histological features of steatosis.

, 2013
Tissue sections of 6 µm thickness were performed on paraffin embedded biopsies from normal liver or from fatty liver and stained with HES (hematoxylin, eosin and safran). Normal hepatic lobule without steatosis (left panel) or fatty liver area exhibiting
François Le Naour (43849), Marie-Pierre Bralet (369950), Catherine Guettier (117122), Paul Dumas (171248), Delphine Debois (223816), Olivier Laprévote (2468284), Alain Brunelle (116857), Christophe Sandt (171217)   +7 more
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Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source