Results 131 to 140 of about 25,057 (234)

Using Optical Lattice for STED Parallelization

open access: yes, 2014
International audienceBeing a scanning microscopy, Stimulated Emission Depletion (STED) needs to be parallelized for fast wide-field imaging. Here, we achieve large parallelization of STED microscopy using well-designed Optical Lattice (OL) for depletion,
Yang, Bin   +2 more
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren   +5 more
wiley   +1 more source

Systemic Nanomechanical Single‐Cell Profiling Reveals Mechanophenotype Transitions Under Therapeutic Perturbation

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku   +4 more
wiley   +1 more source

Molecular Machine‐Driven Fluorogenic Probes for Motion–Signal Conversion and Hydrophilicity Retention in Live‐Cell Nanoscopy

open access: yesAggregate, Volume 7, Issue 10, October 2026.
A hydrophilicity‐retention strategy for developing fluorogenic probes by conjugating malachite green (as the molecular motion switch) with a spirocyclization‐free rhodamine (as the signal module) was developed for nanoscopic imaging of mitochondrial cristae structures and dynamics in living cells.
Yuan Luo   +15 more
wiley   +1 more source

Interplay Between Epigenetics and Reactive Oxygen Species in Tumor Radioresistance: Mechanisms and Therapeutic Strategies for Radiotherapy

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Radiotherapy efficacy is constrained by tumor radioresistance, which arises in part from the interplay between reactive oxygen species (ROS) and epigenetic regulation. This review systematically synthesizes the bidirectional “epigenetics‐ROS interactive network” that governs tumor radiosensitivity. We propose that this network operates through
Zhengmao Yang   +5 more
wiley   +1 more source

Litteratur, sted og historie

open access: yes, 2012
En kritisk refleksion over forskningsarbejdet i min afhandling, Hvor litteraturen finder sted, 2001 ...
Mai, Anne-Marie
core   +1 more source

Two‐Photon Fluorescence and Second‐Harmonic Generation Microscopy: Principles and Biomedical Applications

open access: yesJournal of Biophotonics, Volume 19, Issue 10, October 2026.
Compared with single‐photon methods, TPM enables deep‐tissue imaging using near‐infrared light, with excitation confined to the focal plane, thereby reducing photodamage. SHG microscopy images noncentrosymmetric biological structures such as collagen and myosin without fluorescent labels, offering direct structural contrast.
Kausalya Neelavara Makkithaya   +7 more
wiley   +1 more source

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 10, October 2026.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo   +5 more
wiley   +1 more source

Active Field Theory Approach to Explain Size Control of Transcriptional Condensates

open access: yesMacromolecular Bioscience, Volume 26, Issue 10, October 2026.
Transcriptional condensates are highly dynamic but resist coarsening in living cells, and high‐resolution microscopy reveals an exponential size distribution in steady state. This size control might be related to reverse Ostwald ripening, a genuine non‐equilibrium mechanism that arrests coarsening.
Kathrin Hertäg   +8 more
wiley   +1 more source

Sted, landskab, rum

open access: yesSlagmark - Tidsskrift for idéhistorie, 2018
The article discusses matters concerning place by way of three prose poems byDanish writer Louis Jensen. The readings understand place by way of the neighbouring concepts of landscape and space. They set out from a phenomenological understanding of place, presenting basic insights of this approach (especially using the works of Edward S.
openaire   +2 more sources

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