Results 31 to 40 of about 1,205,200 (315)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

DEFECT «TRACKS FROM CUTS ON ROLLERS» ON THE EXTERNAL SURFACE OF SEAMLESS HOTROLLED PIPES

open access: yesЛитьë и металлургия, 2012
The defect, revealed on an external surface of sleeves at piercing of slug at piercing mill of helical rolling of construction «СТР100VD» with twin-pillar rollers of mushroom shape and guiding disks of Disher, is considered.
I. A. Kovalyova   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

APPLICATION OF MONO-TUBES FOR CIRCULATING VACUUMATOR

open access: yesЛитьë и металлургия, 2007
The fittings furnace- bowl and circulating vacuumuator are used at RUP “B M Z” in ESPTs-I for ladle processing of steel.
I. A. Bondarenko   +5 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On the alloys of steel [PDF]

open access: yesAbstracts of the Papers Printed in the Philosophical Transactions of the Royal Society of London
Abstract The metals which form the most valuable alloys with steel, for the purpose of manufacture into cutting instruments, are silver, platinum, rhodium, iridium, osmium, and palladium. Eight pounds of Indian steel, alloyed with 1/1000th of pure silver, formed a very hard and tenacious compound, well adapted to the manufacture of ...
Stodart, J., Faraday, M.
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

ASSIMILATION OF THE TECHNOLOGY OF THE STEEL REFINING BY POWDERY MATERIALS AT THE AGGREGATE “BOWL-FURNACE”

open access: yesЛитьë и металлургия, 2005
The technology of the steel refining by powder materials at the unit “bowl-furnace” is presented.
V. S. Pishikln   +5 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

ABOUT THE POSSIBILITY OF THE METAL OF CORD QUALITY PRODUCTION WITHOUT USING OF VACUUMATOR ON THE FIRST LINE OF RUP “BMZ”

open access: yesЛитьë и металлургия, 2004
The new approach to the description of the nonmetallics elimination process in the process of the out-of -furnace processing using hydrodynamic and physical-chemical models is offered. The possibility of control of the nonmetallics elimination process in
S. V. Kazakov   +5 more
doaj  

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