Results 41 to 50 of about 991,242 (315)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Perfection of the regime of deoxidation and out-of-fumace processing of cord steel on the basis of information on oxidability of metal

Литьë и металлургия, 2002
There is developed and introduced the new technology of cord steels production with metal processing by slags of certain constitution and carbon deoxidation at vacuum degasing, that allowed to reduce the pollution of steel with nonmetallics.
V. V. Enders, M. P. Gulajev, D. S. Jakshuk, V. V. Pivtsajev, V. Ju. Gunenkov   +4 more
doaj  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

APPLICATION OF MONO-TUBES FOR CIRCULATING VACUUMATOR

Литьë и металлургия, 2007
The fittings furnace- bowl and circulating vacuumuator are used at RUP “B M Z” in ESPTs-I for ladle processing of steel.
I. A. Bondarenko, M. V. Murikov, A. I. Nosovets, V. M. Nosovets, A. V. Olenchenko, I. I. Shkuljkova   +5 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Effect of interlamellar spacing on the elastoplastic behavior of C70 pearlitic steel: Experimental results and self-consistent modeling [PDF]

, 2014
The effect of pearlite microstructure characteristics on strength and deformation of C70 pearlitic steel was investigated. Tensile tests under X-ray diffraction coupled with self-consistent model have been used to identify the role of interlamellar ...
BACZMANSKI, Andrzej, Baczmanski, A., YAHYAOUI, Houda, SIDHOM, H, BRAHAM, Chedly   +4 more
core   +1 more source

ASSIMILATION OF THE TECHNOLOGY OF THE STEEL REFINING BY POWDERY MATERIALS AT THE AGGREGATE “BOWL-FURNACE”

Литьë и металлургия, 2005
The technology of the steel refining by powder materials at the unit “bowl-furnace” is presented.
V. S. Pishikln, A. V. Kovalev, S. E. Grinberg, V. P. Stets, F. G. Gareev, A. S. Zazjan   +5 more
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source