Results 51 to 60 of about 2,610,566 (293)
Литьë и металлургия, 2005 The technology of the steel refining by powder materials at the unit “bowl-furnace” is presented.
V. S. Pishikln +5 more
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Литьë и металлургия, 2004 The new approach to the description of the nonmetallics elimination process in the process of the out-of -furnace processing using hydrodynamic and physical-chemical models is offered. The possibility of control of the nonmetallics elimination process in
S. V. Kazakov +5 more
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
PROBLEMS OF MIGRATION OF WIRES OF THE METAL CORD INSIDE LAYERS OF COMPACT CONSTRUCTIONS
Литьë и металлургия, 2012 It is shown that at manufacture of metal cord of compact constructions there is a possibility to control by various processing methods the inclination of metal cord layers to migration.
A. V. Vedeneev +3 more
doaj +1 more source
Steel: Past the Crossroads [PDF]
, 1983 [Excerpt] A majority of the 154,532 steelworkers who are presently laid off will never go back to work. They will be shut out of the steel industry because the steel companies have a new game plan.
DuBois, Tom
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Reconstructing fully-resolved trees from triplet cover distances [PDF]
, 2014 It is a classical result that any finite tree with positively weighted edges, and without vertices of degree 2, is uniquely determined by the weighted path distance between each pair of leaves.
Huber, Katharina T., Steel, Mike
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source