Results 51 to 60 of about 3,207,999 (341)

A Hamiltonian treatment of stimulated Brillouin scattering in nanoscale integrated waveguides

, 2015
We present a multimode Hamiltonian formulation for the problem of opto-acoustic interactions in optical waveguides. We establish a Hamiltonian representation of the acoustic field and then introduce a full system with a simple opto-acoustic coupling that
Sipe, J. E., Steel, M. J.
core   +1 more source

Wettability characteristics of carbon steel modified with CO2, Nd:YAG, Excimer and high power diode lasers [PDF]

, 2000
Interaction of CO2, Nd:YAG, excimer and high power diode laser (HPDL) radiation with the surface of a common mild steel (EN8) was found to effect changes in the wettability characteristics of the steel, namely changes in the measured contact angle ...
Agathopoulos, Bradley, Chen, Dausinger, Dyer, Fowkes, Good, Heitz, Henari, J. Lawrence, Kokai, L. Li, Lawrence, Lawrence, Lawrence, Li, Nicolas, Olfert, Schmidt, Shuttleworth, Ueki, Zhou, Zhou   +22 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

ABOUT THE POSSIBILITY OF THE METAL OF CORD QUALITY PRODUCTION WITHOUT USING OF VACUUMATOR ON THE FIRST LINE OF RUP “BMZ”

Литьë и металлургия, 2004
The new approach to the description of the nonmetallics elimination process in the process of the out-of -furnace processing using hydrodynamic and physical-chemical models is offered. The possibility of control of the nonmetallics elimination process in
S. V. Kazakov, V. Ju. Gunenkov, I. V. Kushnerev, P. V. Bizukov, V. A. Matochkin, N. V. Andrianov   +5 more
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

ASSIMILATION OF THE TECHNOLOGY OF THE STEEL REFINING BY POWDERY MATERIALS AT THE AGGREGATE “BOWL-FURNACE”

Литьë и металлургия, 2005
The technology of the steel refining by powder materials at the unit “bowl-furnace” is presented.
V. S. Pishikln, A. V. Kovalev, S. E. Grinberg, V. P. Stets, F. G. Gareev, A. S. Zazjan   +5 more
doaj  

The selection of subcontractors: is price the major factor? [PDF]

, 2007
The philosophy of ‘lowest price wins’ in the selection of subcontractors often leads to problems with quality of work and claims for further costs. Since Latham (1994), many models have offered selection methods that take account of a wide range of ...
Hendry, Jason, Lavelle, Derek, Steel, Glenn   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

PROBLEMS OF MIGRATION OF WIRES OF THE METAL CORD INSIDE LAYERS OF COMPACT CONSTRUCTIONS

Литьë и металлургия, 2012
It is shown that at manufacture of metal cord of compact constructions there is a possibility to control by various processing methods the inclination of metal cord layers to migration.
A. V. Vedeneev, Ju. V. Feoktistov, B. A. Birjukov, V. I. Gritsaenko   +3 more
doaj   +1 more source