Results 61 to 70 of about 171,553 (219)

Electrolytic Plasma Nitriding of Medium-Carbon Steel 45 for Performance Enhancement

Crystals
This article analyzes the effect of electrolytic plasma nitriding on the performance of medium-carbon steel 45 under increased mechanical loads and in aggressive environments. Nitrided samples in carbamide electrolytes, both with and without the addition
Zarina Satbayeva, Almasbek Maulit, Nurlybek Ispulov, Daryn Baizhan, Bauyrzhan Rakhadilov, Rinat Kusainov   +5 more
doaj   +1 more source

Quenching and tempering parameter on Indonesian hot rolled plate steel for armour steel

MATEC Web of Conferences, 2018
Armour steel is a high strength and hardness steel used to protect damage by an object, individual or vehicle from the direct pressure of projectile. This steel used for military and commercials equipment in Indonesia and produced out of hot rolled plate
Yurianto, Pratikto, Sonoko Rudy, Wahyono, Bayuseno A.P.   +4 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Influence of Material in Circular Splines of Harmonic Reducers on Wear Resistance

Jixie chuandong
Three kinds of circular spline materials are studied for harmonic reducers, stainless steel 2Cr13, medium carbon alloy steel 40Cr, carbon 45 steel. Through the analysis of microstructure, hardness, three-dimensional and two-dimensional morphology in ...
Mu Xiaobiao, Ge Yi, Gao Mingyan, Yang Guoqiang, Zhang Chaolei   +4 more
doaj  

Galvanic corrosion behavior of AZ91D alloy / 45 steel couple under magnetic field

Journal of Magnesium and Alloys
Galvanic corrosion behavior of AZ91D alloy / 45 steel couple in 3.5 wt.% NaCl solution under 0, 0.2 and 0.4 T magnetic field were studied by microstructure observation, immersion test and electrochemical measurement.
Xin Zhang, Wan Mei, Zehua Zhou, Shaoqun Jiang, Gang Wang, Xiangru Shi, Zehua Wang   +6 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Research and Development of Steel T27 for Railway

Teshugang, 2008
The steel T27(0. 10~0. 16C,0. 15~0.25Cr,0.025～0.045Al)for railway belongs in peritectic steels which was produced by 45%～60% hot metal + scrap-50tEAF-LF(VD)-caster flow sheet at special steel plant,Lai  Steel.
叶黎华, 马佐仓, 梁建国, 范夕荣, 马传庆   +4 more
doaj  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source