Results 51 to 60 of about 1,426,883 (305)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Field Evaluation of Elliptical Fiber Reinforced Polymer Dowel Performance, June 2005 [PDF]

open access: yes, 2005
Fiber reinforced polymer (FRP) composite materials are making an entry into the construction market in both buildings and pavements. The application to pavements so far has come in the form of joint reinforcement (dowels and tie bars).

core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Development and Performance Evaluation of a Mechanical Connection for Steel and Shape Memory Alloy Bars

open access: yesMetals
Shape memory alloys (SMAs) demonstrate a shape memory effect and superelasticity that can provide recovery performance to structural members. In this study, a round SMA bar was designed to replace the conventional deformed steel bar, particularly within ...
Min-Kyu Song, Eunsoo Choi, Jong-Han Lee
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Careers with Bethlehem Steel: and the Loop Course

open access: yes, 1955
This book discusses the career opportunities for college men seeking employment with in the Bethlehem Steel Company. Specifically the book discusses the Bethlehem Loop Course, which was established to give employees straight out of college the ...

core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

[Report] Bethlehem Steel Company : employees of Bethlehem Steel Company : with their salaries and wages

open access: yes, 1901
This is a report of the employees of the Bethlehem Steel Company, along with wages and salaries from 1901. The report provides statistical data about the employees at the Bethlehem Steel, specifically detailing the number of workers employed per "class ...

core  

Experimental Study of the Mechanical Behavior of a Steel Arch Structure Used in the Main Lining of a Highway Tunnel

open access: yesBuildings
The steel rib and the lattice girder are two typical steel arch frames used in the primary lining of the New Austrian Tunnelling Method (NATM) highway tunnel.
Changjun Li   +8 more
doaj   +1 more source

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