Results 61 to 70 of about 79,046 (254)

Investigation of HYSD Steel Bars and GFRP Bars

open access: yesINTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
The evolving demands of modern construction, especially in corrosive and high-performance environments, have led to the exploration of alternative reinforcement materials beyond traditional steel. This research investigates the mechanical behavior, bond performance, and environmental durability of High Yield Strength Deformed (HYSD) steel bars and ...
openaire   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Corrosion of Steel Reinforcements in Fly Ash- and Kaolin-based Geopolymer Concrete Immersed in Distilled Water and ASTM Seawater

open access: yesCivil Engineering Dimension, 2013
Corrosion behavior of steel bar in fly ash- and kaolin-based geopolymer concrete immersed in aggressive media of distilled water and ASTM seawater was compared to Portland cement concrete having similar mix design.
Astutiningsih S.   +2 more
doaj  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Cause Analysis and Improvement Measures of Unqualified Flaw Detection of H13 Steel Φ130 ~ 150 mm Hot Rolled Bar

open access: yesTeshugang, 2022
By comparison and analysis on the chemical composition, production process and inspection qualification rate of 中 130-150 mm hot rolled bar of H13 steel and H11 steel, it is pointed out that average vanadium content in steel increasing from 0.5% to 1.0 ...
张新文   +3 more
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Finite Element Analysis on Temperature Field of Finishing Rolled 20CrMnTiH Steel Round Bar during Controlled Cooling

open access: yesTeshugang, 2007
The temperature distribution curves at core, 1/2 radius and surface of the Φ35 mm round bar of 20CrMnTiH steel have been got by finite element simulating and situ temperature measuring to finishing rolled round steel bar during controlled cooling ...
程满   +4 more
doaj  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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