Results 51 to 60 of about 90,749 (265)

A fundamental study of dynamic behavior of vehicles with unstable region under force control

open access: yesNihon Kikai Gakkai ronbunshu, 2015
The primary method of improving steering dynamic response performance is expected to involve position control. However the driver uses not only the position of the steering wheel but also torque for control.
Hideki SAKAI
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A consideration to natural frequencies under force control

open access: yesNihon Kikai Gakkai ronbunshu, 2015
For characterizing vehicle dynamic behavior, the natural frequency and the damping ratio under position control, that is the control using steering angle as driver's input, have been developed as representative indices.
Hideki SAKAI
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Modelling and Simulation of a Hydrostatic Steering System for Agricultural Tractors

open access: yesEnergies, 2018
The steering system of a vehicle impacts on the vehicle performance, safety and on the driver’s comfort. Moreover, in off-road vehicles using hydrostatic steering systems, the energy dissipation also becomes a critical issue.
Barbara Zardin   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Estimation of noise radiation including airborne noise using the in-situ blocked force approach (Third report, experimental verification of the estimation method by application to rattle noise from an electric power steering system)

open access: yesNihon Kikai Gakkai ronbunshu, 2020
In the previous reports, a methodology for estimating noise radiation including airborne noise from a mechanical system under the operational condition by component test of a certain active subsystem using the in-situ blocked force approach, which is ...
Yoshihiro SATO   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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