Dynamic interpersonal therapy for moderate to severe depression: A pilot randomized controlled and feasibility trial [PDF]
Background: Improving Access to Psychological Therapies (IAPT) services treat most patients in England who present to primary care with major depression. Psychodynamic psychotherapy is one of the psychotherapies offered.
Allison, E. +10 more
core +2 more sources
Intrinsic structural disorder in cytoskeletal proteins. [PDF]
Cytoskeleton, the internal scaffold of the cell, displays an exceptional combination of stability and dynamics. It is composed of three major filamentous networks, microfilaments (actin filaments), intermediate filaments (neurofilaments), and ...
Beata Szabo +4 more
core +1 more source
Rare Presentation of a Rare Orthopedic Pathology: Erdheim Chester Disease [PDF]
In 1930, William Chester and pathologist Jakob Erdheim discovered the pathology currently known as Erdheim Chester disease. There are only approximately 249 histologically confirmed patients to have been diagnosed with this disease as noted in the ...
Samona J, Owen J, Martin S
core +1 more source
Legionella pneumophila: an aquatic microbe goes astray [PDF]
Legionella pneumophila is naturally found in fresh water were the bacteria parasitize within protozoa. It also survives planctonically in water or biofilms. Upon aerosol formation via man-made water systems, L.
Hacker, Jörg +2 more
core +1 more source
The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]
BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E. +9 more
core +3 more sources
Complete Genome Sequences of Paenibacillus Larvae Phages BN12, Dragolir, Kiel007, Leyra, Likha, Pagassa, PBL1c, and Tadhana [PDF]
We present here the complete genomes of eight phages that infect Paenibacillus larvae, the causative agent of American foulbrood in honeybees. Phage PBL1c was originally isolated in 1984 from a P.
Berg, Jordan A. +22 more
core +2 more sources
Hijacking translation in addiction. [PDF]
Two studies suggest that the reduced activity of a translation initiation factor called eIF2α might be partly responsible for the increased risk of drug addiction seen in ...
Izquierdo, Alicia, Silva, Alcino J
core +1 more source
Is there a causal association between genotoxicity and the imposex effect? [PDF]
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Josephine A. Hagger +13 more
core +1 more source
Pattern Dystrophy of the Macula in a Case of Steinert Disease [PDF]
IntroductionMyotonic dystrophies are typically associated with ocular complications like ptosis, weakness of the ocular muscle and cataracts, but also with less recognized retinal changes.Case ReportA 41-year-old female with type 1 myotonic dystrophy ...
Dolz-Marco, Rosa +4 more
core +2 more sources
ER Stress-Induced eIF2-alpha Phosphorylation Underlies Sensitivity of Striatal Neurons to Pathogenic Huntingtin [PDF]
A hallmark of Huntington's disease is the pronounced sensitivity of striatal neurons to polyglutamine-expanded huntingtin expression. Here we show that cultured striatal cells and murine brain striatum have remarkably low levels of phosphorylation of ...
Ashery, U. +6 more
core +7 more sources

