Results 121 to 130 of about 63,717 (277)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Iron Snails: Nonequilibrium Dynamics and Spiral Abundance Patterns

open access: yesThe Astrophysical Journal
Galaxies are not in a dynamical steady state: they continually undergo perturbations, e.g., from infalling dwarf galaxies and dark matter substructure. After a dynamical perturbation, stars phase mix toward a new steady state; in so doing, they generally
Neige Frankel   +4 more
doaj   +1 more source

Can we trust elemental abundances derived in late-type giants with the classical 1D stellar atmosphere models? [PDF]

open access: bronze, 2009
A. Kučinskas   +15 more
openalex   +1 more source

Chemical abundances of 1111 FGK stars from the HARPS GTO planet search program IV. Carbon and C/O ratios for Galactic stellar populations and planet hosts [PDF]

open access: green, 2021
E. Delgado Mena   +6 more
openalex   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Chemical Abundances in the Leiptr Stellar Stream: A Disrupted Ultra-faint Dwarf Galaxy?

open access: yesThe Open Journal of Astrophysics
Chemical abundances of stellar streams can be used to determine the nature of a stream's progenitor. Here we study the progenitor of the recently discovered Leiptr stellar stream, which was previously suggested to be a tidally disrupted halo globular ...
Kaia R. Atzberger   +13 more
doaj   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

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