Results 131 to 140 of about 63,717 (277)

The Stellar Abundances and Galactic Evolution Survey (SAGES) III -- The g/r/i-band Data Release [PDF]

open access: green
Chun Li   +17 more
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

Observations of the Ultraviolet-bright Star ZNG 1 in the Globular Cluster M5 (NGC 5904)

open access: yesThe Astronomical Journal
We have analyzed archival spectra of the hot UV-bright star ZNG 1 in the globular cluster M5 (NGC 5904) obtained with the Far Ultraviolet Spectroscopic Explorer and the Space Telescope Imaging Spectrograph.
William V. Dixon
doaj   +1 more source

Unveiling the (in)consistencies among the galaxy stellar mass function, star formation histories, satellite abundances, and intracluster light from a semi-empirical perspective [PDF]

open access: gold
Hao Fu   +18 more
openalex   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Investigating Non-LTE Abundances of Neodymium in Metal-poor FGK Stars

open access: yesThe Astrophysical Journal
The dominant site(s) of the r -process are a subject of current debate. Ejecta from r -process-enrichment events like kilonovae are difficult to directly measure, so we must instead probe abundances in metal-poor stars to constrain r -process models ...
John D. Dixon   +5 more
doaj   +1 more source

The Galactic Thick Disk Stellar Abundances

open access: green, 2021
J. X. Prochaska   +4 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

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