Results 131 to 140 of about 876,778 (355)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

The Impact of Initial Composition on Massive Star Evolution and Nucleosynthesis

open access: yesThe Astrophysical Journal
We study the sensitivity of presupernova evolution and supernova nucleosynthesis yields of massive stars to variations of the initial composition. We use the solar abundances from Lodders, and compute two different sets of initial stellar compositions ...
Christopher West   +4 more
doaj   +1 more source

Stellar Abundances In The Solar Neighborhood

open access: yes, 2012
The only elements that were made in significant quantity during the Big Bang were hydrogen and helium, and to a lesser extent lithium. Depending on the initial mass of a star, it may eject some or all of the unique, newly formed elements into the interstellar medium.
openaire   +2 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

The halo+cluster system of the Galactic globular cluster NGC1851

open access: yes, 2014
NGC1851 is surrounded by a stellar component that extends more than ten times beyond the tidal radius. Although the nature of this stellar structure is not known, it has been suggested to be a sparse halo of stars or associated with a stellar stream.
Angeloni, R.   +19 more
core   +1 more source

Blue Supergiants in the Pinwheel Galaxy M101: Comparison with H II Region Chemical Abundances, Spectroscopic Distance, and an Independent Determination of the Hubble Constant

open access: yesThe Astrophysical Journal
We present a quantitative spectroscopic study of 13 blue supergiant stars in the Pinwheel Galaxy M101, based on data obtained with the Low Resolution Imaging Spectrometer available at the Keck I telescope.
Fabio Bresolin   +4 more
doaj   +1 more source

Stellar parameters and chemical abundances of 223 evolved stars with and without planets [PDF]

open access: yes, 2014
Aims. We present fundamental stellar parameters, chemical abundances, and rotational velocities for a sample of 86 evolved stars with planets (56 giants; 30 subgiants), and for a control sample of 137 stars (101 giants; 36 subgiants) without planets. The
E. Jofr'e   +7 more
semanticscholar   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Nucleosynthesis: Stellar and Solar Abundances and Atomic Data [PDF]

open access: yes, 2006
Abundance observations indicate the presence of often surprisingly large amounts of neutron capture (i.e., s- and r-process) elements in old Galactic halo and globular cluster stars.
Collier, Jason   +5 more
core   +4 more sources

Boron Abundances in Early B Dwarfs of the Galactic Open Cluster NGC 3293

open access: yesThe Astrophysical Journal
New boron abundances or upper limits have been determined for eight early B stars in the young Galactic open cluster NGC 3293, using UV spectra obtained by the Hubble Space Telescope Cosmic Origins Spectrograph.
Charles R. Proffitt   +6 more
doaj   +1 more source

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