Results 91 to 100 of about 2,560 (288)

Rotational Evolution of Classical T Tauri Stars: Models and Observations

open access: yesThe Astrophysical Journal
We developed a grid of stellar rotation models for low-mass and solar-type classical T Tauri stars (CTTS; 0.3 M _⊙ < M _* < 1.2 M _⊙ ). These models incorporate the star–disk interaction and magnetospheric ejections to investigate the evolution of the ...
Javier Serna   +19 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Merger-driven Growth of Intermediate-mass Black Holes: Constraints from Hubble Space Telescope Imaging of Hyper-luminous X-Ray Sources

open access: yesThe Astrophysical Journal
Hyper-luminous X-ray sources (HLXs) are extragalactic off-nuclear X-ray sources with luminosities exceeding the theoretical limit for accretion onto stellar-mass compact objects.
R. Scott Barrows   +3 more
doaj   +1 more source

Planetary accretion debris and IR excesses in open stellar clusters [PDF]

open access: bronze, 2008
D. E. Backman   +2 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Accretion in supergiant High Mass X-ray Binaries

open access: yesEPJ Web of Conferences, 2014
Supergiant High Mass X-ray Binary systems (sgHMXBs) consist of a massive, late type, star and a neutron star. The massive stars exhibits strong, radiatively driven, stellar winds.
Manousakis Antonios   +2 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Constraining Wind-driven Accretion onto Gaia BH3 with Chandra

open access: yesThe Astrophysical Journal
Gaia BH3 is the most massive known stellar-origin black hole in the Milky Way, with a mass M _• ≈ 33 M _⊙ . Detected from Gaia’s astrometry, this black hole is in the mass range of those observed via gravitational waves, whose nature is still highly ...
Nico Cappelluti   +2 more
doaj   +1 more source

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