Results 141 to 150 of about 91,199 (294)

Accretion of Active Galactic Nucleus Stars Under the Influence of Disk Geometry

open access: yesThe Astrophysical Journal
Massive stars can form within or be captured by active galactic nucleus disks, influencing both the thermal structure and metallicity of the disk environment.
Yi-Xian Chen   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A MaNGA about the Legacy. I. Connecting the Assembly of Stellar Halo with the Average Star Formation History in Low-redshift Massive Galaxies

open access: yesThe Astronomical Journal
We investigate the connection between stellar mass distribution, assembly history, and star formation timescales in low-redshift massive early-type galaxies (ETGs) by combining deep LegacySurvey imaging with MaNGA’s spatially resolved spectroscopy ...
Xiaoya Zhang, Song Huang, Meng Gu
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Magnetized Accretion Flows: The Key Roles of Viscosity and Black Hole Mass

open access: yesThe Astrophysical Journal
In our previous work, we constructed a black hole accretion model incorporating magnetic fields and disk winds. However, this model was derived under conditions of a small viscosity parameter α ( α < α _crit , where α _crit is the critical viscosity ...
Wen-Biao Wu
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Accretion and Stellar Energy [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1940
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Diverse Pathways for Supermassive Black Hole–Galaxy Coevolution

open access: yesThe Astrophysical Journal
Supermassive black holes (SMBHs) are observed in diverse galaxy populations across cosmic time, yet a clear understanding of how they coevolve with their hosts has not been reached.
Bryan A. Terrazas   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy