Results 71 to 80 of about 323,430 (318)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Planet Formation Regulated by Galactic-scale Interstellar Turbulence

The Astrophysical Journal Letters
Planet formation occurs over a few Myr within protoplanetary disks of dust and gas, which are often assumed to evolve in isolation. However, extended gaseous structures have been uncovered around many protoplanetary disks, suggestive of late-stage infall
Andrew J. Winter, Myriam Benisty, Sean M. Andrews   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Evolution of the Accretion Rate of Young Intermediate-mass Stars: Implications for Disk Evolution and Planet Formation

The Astronomical Journal
This work presents a study of the evolution of the stellar accretion rates of pre-main-sequence intermediate-mass stars. We compare the accretion rate of the younger intermediate-mass T Tauri stars (IMTTSs) with the older Herbig stars into which they ...
Sean D. Brittain, Joshua W. Kern, Gwendolyn Meeus, René D. Oudmaijer   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Stellar Evolution with Radiative Feedback in AGN Disks

The Astrophysical Journal
Stars embedded in the inner parsec region of an active galactic nucleus (AGN) experience extreme accretion conditions that significantly alter their evolution.
Zheng-Hao Xu, Yi-Xian Chen, Douglas N. C. Lin   +2 more
doaj   +1 more source

Constraints from Dust Mass and Mass Accretion Rate Measurements on Angular Momentum Transport in Protoplanetary Disks [PDF]

, 2017
In this paper, we investigate the relation between disk mass and mass accretion rate to constrain the mechanism of angular momentum transport in protoplanetary disks.
G. Mulders, I. Pascucci, C. Manara, L. Testi, G. Herczeg, T. Henning, S. Mohanty, G. Lodato   +7 more
semanticscholar   +1 more source

A Lagrangian model for dust evolution in protoplanetary disks: formation of wet and dry planetesimals at different stellar masses [PDF]

Astronomy & Astrophysics, 2018
We introduce a new Lagrangian smooth-particle method to model the growth and drift of pebbles in protoplanetary disks. The Lagrangian nature of the model makes it especially suited to following characteristics of individual (groups of) particles, such as
D. Schoonenberg, C. Ormel, S. Krijt
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Semi-analytical Model for Stellar Evolution in AGN Disks

The Astrophysical Journal
Disks of gas accreting onto supermassive black holes may host numerous stellar-mass objects, formed within the disk or captured from a nuclear star cluster.
Alexander J. Dittmann, Matteo Cantiello
doaj   +1 more source