Results 241 to 250 of about 130,683 (338)
Magnetic star-planet interaction in the young exoplanet system DS Tucanae Ab
Santos Ld, Owen J, Duvvuri G, Loyd ROP, Vidotto A, Presa A, Bourrier V, King G, Airapetian V, Ehrenreich D, France K, Lendl M, Lothringer J, Nielsen L. +13 moreeuropepmc +1 more sourcePerspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman +13 morewiley +1 more sourceTranscriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more sourcePotential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk +4 morewiley +1 more sourceExploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair +17 morewiley +1 more sourceNeutron capture measurements for s-process nucleosynthesis: A review about CERN n_TOF developments and contributions. [PDF]
Eur Phys J A Hadron NuclDomingo-Pardo C, Aberle O, Alcayne V, Alpar G, Halabi MA, Amaducci S, Babiano V, Bacak M, Balibrea-Correa J, Bartolomé J, Bernardes AP, Gameiro BB, Berthoumieux E, Beyer R, Birch M, Boromiza M, Bosnar D, Brusasco B, Caamaño M, Cahuzac A, Calviño F, Calviani M, Cano-Ott D, Casanovas A, Castelluccio DM, Catlett D, Cerutti F, Cescutti G, Chiaveri E, Claps G, Colombetti P, Colonna N, Camprini PC, Cortés G, Cortés-Giraldo MA, Cosentino L, Cristallo S, D'Ottavi A, de la Fuente Rosales G, Dellmann SF, Diakaki M, Di Castro M, Di Chicco A, Dietz M, Dupont E, Durán I, Eleme Z, Eslami M, Fargier S, Fernández-Domínguez B, Finocchiaro P, Flanagan W, Furman V, Gandhi A, García-Infantes F, Gawlik-Ramiega A, Gervino G, Gilardoni S, González-Romero E, Goula S, Griesmayer E, Guerrero C, Gunsing F, Gustavino C, Heyse J, Hillman W, Jenkins DG, Jericha E, Junghans A, Kadi Y, Kaperoni K, Kelly I, Kokkoris M, Kopatch Y, Krtička M, Kyritsis N, Lederer-Woods C, Lerendegui-Marco J, Manna A, Martínez T, Martínez-Cañada M, Masi A, Massimi C, Mastinu P, Mastromarco M, Maugeri EA, Mazzone A, Mendoza E, Mengoni A, Michalopoulou V, Milazzo PM, Moldenhauer J, Mucciola R, González EM, Musumarra A, Negret A, Odusina E, Papanikolaou D, Patronis N, Pavón-Rodríguez JA, Pellegriti MG, Pérez-Maroto P, de Rada Fiol AP, Perfetto G, Perkowski J, Petrone C, Pieretti N, Piersanti L, Pirovano E, Porras I, Praena J, Quesada JM, Reifarth R, Rochman D, Romanets Y, Rooney A, Rovira G, Rubbia C, Sánchez-Caballero A, Sahoo RN, Scarpa D, Schillebeeckx P, Smith AG, Sosnin NV, Spelta M, Stamati ME, Stasiak K, Tagliente G, Tarifeño-Saldivia A, Tarrío D, Torres-Sánchez P, Tosi S, Tsiledakis G, Valenta S, Vaz P, Vecchio G, Vescovi D, Vlachoudis V, Vlastou R, Wallner A, Weiss C, Woods PJ, Wright T, Wu R, Žugec P, The n_TOF Collaboration. +145 moreeuropepmc +1 more source