Results 41 to 50 of about 7,344 (264)
Core-envelope Decoupling Drives Radial Shear Dynamos in Cool Stars
Differential rotation is thought to be responsible for the dynamo process in stars like our Sun, driving magnetic activity and starspots. We report that starspot measurements in the Praesepe open cluster are strongly enhanced only for stars that depart ...
Lyra Cao +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Revisiting ϵ Eridani with NEID: Identifying New Activity-sensitive Lines in a Young K Dwarf Star
Recent improvements in the sensitivity and precision of the radial velocity (RV) method for exoplanets have brought it close, but not quite to, the threshold (∼10 cm s ^−1 ) required to detect Earth-mass and other potentially habitable planets around Sun-
Sarah Jiang +9 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
In the Trenches of the Solar–Stellar Connection. VII. Wilson–Bappu 2022
The Wilson–Bappu effect (WBE) is a remarkable correlation between the width of the chromospheric emission core of the Ca ii 3934 Å K line and stellar absolute visual magnitude over an astonishing range, from diminutive red dwarfs to bloated yellow ...
Thomas Ayres
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
In this study, we present a comprehensive study of more than 50,000 spectra of 32,257 eclipsing binaries from the LAMOST DR10 survey, including 5200 systems with spectroscopy.
Ansong Shi +9 more
doaj +1 more source

