Results 51 to 60 of about 7,344 (264)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Chromospheric Modeling of the Active M3V Star G 80–21 with RH1.5D

The Astrophysical Journal
This study investigates the active regions of the M3.0V star G 80–21 using the observed data from the CARMENES project with synthetic spectra generated by the RH1.5D radiative transfer code.
Shuai Liu, Huigang Wei, Jianrong Shi, Wenxian Li, Henggeng Han, Jifeng Liu, Shangbin Yang   +6 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Analyzing the Morphology of Late-phase Stellar Flares from G-, K-, and M-type Stars

The Astrophysical Journal
Stellar flares occasionally present a peak-bump light-curve morphology, consisting of an initial impulsive phase followed by a gradual late phase.
Denise G. Yudovich, Kai E. Yang, Xudong Sun   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Searching for Stellar Activity Cycles Using Flares: The Short- and Long-timescale Activity Variations of TIC-272272592

The Astronomical Journal
We examine 4 yr of Kepler 30 minutes data, and five sectors of Transiting Exoplanet Survey Satellite 2 minutes data for the dM3 star KIC-8507979/TIC-272272592. This rapidly rotating ( P = 1.2 day) star has previously been identified as flare active, with
Tobin M. Wainer, James R. A. Davenport, Guadalupe Tovar Mendoza, Adina D. Feinstein, Tom Wagg   +4 more
doaj   +1 more source

Photometric magnetic-activity metrics tested with the Sun: application to Kepler M dwarfs

Journal of Space Weather and Space Climate, 2014
The Kepler mission has been providing high-quality photometric data leading to many breakthroughs in the exoplanet search and in stellar physics. Stellar magnetic activity results from the interaction between rotation, convection, and magnetic field ...
Mathur Savita, Salabert David, García Rafael A., Ceillier Tugdual   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Properties of Flare Quasiperiodic Pulsations Based on a New TESS Flare Catalog

The Astrophysical Journal Supplement Series
Stellar flares are important indicators of stellar magnetic activity and have been widely studied. Detailed studies of flares have raised new questions. For example, the quasiperiodic pulsation (QPP) phenomenon in flares challenges standard flare models,
Yinpeng Wang, Li-yun Zhang, Tianhao Su, Prabhakar Misra, Xianming L. Han   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source