Results 81 to 90 of about 7,344 (264)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Correcting Exoplanet Transmission Spectra for Stellar Activity with an Optimized Retrieval Framework
The Astrophysical JournalThe chromatic contamination that arises from photospheric heterogeneities, e.g., spots and faculae on the host star presents a significant noise source for exoplanet transmission spectra.
Alexandra Thompson +9 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Astrophysical JournalThe primary objective of this study is to develop a time-dependent model of the flaring atmosphere based on observational data. Here, we present, for the first time, a comparison between numerical simulations of the flaring emission, specifically ...
Krzysztof Radziszewski +6 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The Astrophysical Journal Supplement SeriesThe Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) data release 10 (DR10) provides over 3 million G-type stellar spectra, which are important for the study of chromospheric activity of solar-like stars.
Tianhao Su +7 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Astronomical JournalWe measured lithium (Li) abundance and instantaneous chromospheric Ca ii HK activity in Hamilton Echelle Spectrograph observations of 211 solar analog field stars, with one objective being potential identification of grand minimum candidates for ongoing ...
Dan Lubin +4 more
doaj +1 more source
Realistic limitations of detecting planets around young active stars
EPJ Web of Conferences, 2013 Current planet hunting methods using the radial velocity method are limited to observing middle-aged main-sequence stars where the signatures of stellar activity are much less than on young stars that have just arrived on the main-sequence.
Pinfield D. +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source