Results 141 to 150 of about 8,281,459 (308)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

FFNN–TabNet: An Enhanced Stellar Age Determination Method Based on TabNet

Applied Sciences
The precise ascertainment of stellar ages is pivotal for astrophysical research into stellar characteristics and galactic dynamics. To address the prevalent challenges of suboptimal accuracy in stellar age determination and limited proficiency in ...
Han Zhang, Yadong Wu, Weihan Zhang, Yuling Zhang   +3 more
doaj   +1 more source

Mapping the stellar age of the Milky Way bulge with the VVV. II. Deep JKs catalogs release based on PSF photometry [PDF]

, 2019
F. Surot, E. Valenti, S. L. Hidalgo, M. Zoccali, O. A. González, E. Sökmen, D. Minniti, M. Rejkuba, P. W. Lucas   +8 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Stellar ages and stellar rotation

, 2016
Ruth Angus
openalex   +2 more sources

Ages and abundances in large-scale stellar discs of nearby S0 galaxies [PDF]

, 2012
О. К. Сильченко, I. S. Proshina, A. P. Shulga, S. E. Koposov   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Planets Across Space and Time (PAST). VIII. Kinematic Characterization and Identification of Radial Velocity Variables for the LAMOST–Gaia–TESS Stars

The Astrophysical Journal Supplement Series
The Transiting Exoplanet Survey Satellite (TESS) has discovered over 6700 nearby exoplanet candidates using the transit method through its all-sky survey.
Di Wu, Di-Chang Chen, Ji-Wei Xie, Ji-Lin Zhou, Hai-Feng Wang, Weikai Zong, Subo Dong, Maosheng Xiang, A-Li Luo   +8 more
doaj   +1 more source

The relationship between accretion disc age and stellar age and its consequences for protostellar discs [PDF]

, 2011
Michael G. Jones, J. E. Pringle, Richard D. Alexander   +2 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source